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Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Understanding hair growth involves complex interactions between molecules and could help treat hair disorders.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Horizontally sectioned scalp biopsies are more reliable for diagnosing hair loss in women when three samples are taken instead of one.

Different types of stem cells and their environments are key to skin repair and maintenance.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Fat cells in the skin help start healing and form important repair cells after injury.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Hair loss occurs due to fewer papillary cells, smaller follicles, and shorter growth phases.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Ruby laser pulses best destroy hair follicles during the growth phase and effectiveness varies with laser intensity; melanin is key for targeting, and timing treatments can improve results.

Understanding the mouse hair cycle is crucial for cancer research.

Targeting hair follicles can improve skin treatments and reduce side effects.

Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.

The document concludes that hair is complex, with a detailed growth cycle, structure, and clinical importance, affecting various scientific and medical fields.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Chemotherapy often causes temporary hair loss, which is distressing and needs better treatment and support.

Hair loss in men treated best with early medication or transplant, new treatments researched.

Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.