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Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Selective breeding caused the unique curly hair in Mangalitza pigs.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

Finasteride metabolites found in pigs match human studies, making pigs a valid model for human drug research.

Niosomes can effectively deliver Superoxide Dismutase to hair follicles, potentially helping prevent hair loss.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

A hydrogel made from pig fat helps wounds heal faster by regenerating skin fat cells.

Gentamicin penetrates pig skin better through open hair follicles than blocked ones.

The document explains how hair is studied in forensics to identify its source and its role in criminal investigations.

OCT can effectively examine and reveal details about human hair and scalp conditions.

New materials help control stem cell growth and specialization for medical applications.

New treatments for vitiligo may focus on protecting melanocyte stem cells from stress and targeting specific pathways involved in the condition.

Most dogs have hair whorls on their chest and limbs, with shelter dogs and short-haired dogs having more chest whorls.

LGR5 is a common marker of hair follicle stem cells in different animals and is important for hair growth and regeneration.

Methotrexate can temporarily suppress certain immune responses without killing immune cells, potentially helping treat autoimmune diseases.

Pigs without the Hairless gene showed skin and thymus changes, useful for studying human hair disorders.

Hairless rats are good for testing anti-inflammatory drugs, similar to haired rats, without needing to remove fur.

The document concludes that understanding hair biology is key to treating hair disorders, with gene therapy showing potential as a future treatment.

Cancer therapy can cause various skin problems, including hair loss, skin darkening, painful hand-foot syndrome, and severe skin damage.

Adult human skin can grow new fine hair follicles after a deep exfoliation treatment.

Pregnancy causes skin changes like darkening, hair thickening, nail changes, and increased risk of skin growths, most of which usually resolve after birth.

Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Men's hair loss is caused by hormones and genes, and can be treated with medication and surgery, while graying is due to aging and has no prevention except dyeing.

The document concludes that using specific tools and tests is essential for identifying the cause of hair loss and deciding on the right treatment.

Supercritical CO2 extraction makes rice bran oil healthier and safer than traditional methods.