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Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Tofacitinib citrate is effective for moderate-to-severe chronic plaque psoriasis but has safety concerns at higher doses.

Apremilast improved symptoms in patients with severe skin conditions.

Platelet-Rich Plasma (PRP) treatment may increase hair growth for genetic hair loss, but more research is needed to confirm this.

Unwanted facial hair significantly impacts over 40% of women's psychological and social well-being, and various treatment options are available.

Platelet-Rich Plasma (PRP) treatment can potentially increase hair density and quality in people with hair loss, but more research is needed to confirm its effectiveness.

Visible light can improve skin disorders and hair loss, but more research is needed to understand long-term effects.

PRP treatment increases hair density and thickness in androgenetic alopecia by 79%.

Early treatment helps stop hair loss in women of color.

Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.

Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.

Some children with localized scleroderma are rarely resistant to methotrexate, and no common profile for resistance was found.

Microneedling is effective for skin rejuvenation and various skin issues, but more research is needed to confirm its safety and effectiveness.

Finasteride and intense pulsed light effectively reduce unwanted facial hair in women, but may not be cost-effective.

Using more minoxidil solution can lead to better hair growth, but people often use only half the recommended amount. Education and motivation can improve results.

The fractional carbon dioxide laser is a safe and effective treatment for alopecia areata and works better than betamethasone valerate cream alone.

No treatment fully stops excessive hair growth in women, but various methods can help manage it effectively.

Apremilast shows promise for several skin conditions but needs more research.

Oral minoxidil can potentially increase hair growth in people suffering from Central Centrifugal Cicatricial Alopecia.

Ixekizumab helps improve life quality, physical ability, and work performance in patients with psoriatic arthritis who haven't used biologic drugs before.

Tofacitinib and adalimumab are promising treatments for cicatricial alopecia with few side effects.

Upadacitinib effectively treated a patient with multiple inflammatory conditions.

Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.

The combination of laser and topical steroids is more effective for treating alopecia areata than topical steroids alone.

Most patients with rheumatoid arthritis continued methotrexate treatment over two years, but those who stopped and restarted experienced more side effects and less improvement.