506 citations,
March 2005 in “The Journal of Clinical Endocrinology and Metabolism” Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.
July 2023 in “The Journal of Clinical Endocrinology and Metabolism” Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.
July 2024 in “Quality in Sport” Combined minoxidil and PRP therapy improves hair growth without affecting physical performance.
14 citations,
January 2008 in “Gene therapy” Gene therapy shows promise for enhancing physical traits but faces ethical, safety, and regulatory challenges.
27 citations,
September 2015 in “PharmaNutrition” Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.
306 citations,
August 2011 in “Journal of cachexia, sarcopenia and muscle” Enobosarm significantly increased muscle mass and improved physical function in elderly men and postmenopausal women without serious side effects.
January 2018 in “Medicinski pregled” Using high doses and multiple drugs with steroids is risky and should be prevented.
34 citations,
December 2012 in “Current Opinion in Clinical Nutrition and Metabolic Care” Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.
2 citations,
January 2016 in “Sarcoma” Inducing survivin in normal tissues can protect against radiation damage.
June 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Gene therapy in mice increased lifespan and improved health without causing cancer.
9 citations,
March 2019 in “European Journal of Sport Science” New signs like changes in blood markers, physical symptoms, and behavioral shifts may help detect hidden steroid use in athletes.
18 citations,
August 2019 in “Nutrients” Eating barley for life may lead to healthier aging in mice.
May 2023 in “BMC Women's Health” Many women who have used performance-enhancing drugs in Finland show high rates of mental health and substance use issues, and most have normal red blood cell counts.
211 citations,
May 2013 in “Journal of Nutrition Health & Aging” MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
95 citations,
April 2013 in “PLOS ONE” Ginseng is possibly safe but its effectiveness is unclear due to poor quality studies and mixed results.
18 citations,
January 2020 in “Journal of Clinical Research in Pediatric Endocrinology” The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.
18 citations,
January 2008 in “Sen'i Gakkaishi” Thioglycolic acid and L-cysteine change hair structure differently during perms, affecting hair strength and curling efficiency.
17 citations,
February 2019 in “Journal of Clinical Medicine” Testosterone replacement therapy should be used for men with low testosterone levels and symptoms of hypogonadism, after careful diagnosis and considering individual needs.
April 2023 in “JMIR Research Protocols” The study aims to create a model to predict health attributes using diverse health data from Japanese adults.
1 citations,
September 2022 in “Journal of Medical Case Reports” Rehabilitation therapy helped a severe COVID-19 patient regain muscle mass and return to normal life.
December 2020 in “Innovation in aging” Rapamycin treatment helps reduce brain inflammation and symptoms of mitochondrial disease by blocking specific pathways in mice.
December 2021 in “Innovation in aging” Frailer men have a higher risk of worsening prostate problems and serious health events needing hospital care.
51 citations,
May 2011 in “Phytotherapy Research” Ginseng, especially red ginseng, may help regrow hair and block a hair loss-related enzyme.
10 citations,
October 2010 in “International Journal of Andrology” Finasteride doesn't affect oral testosterone undecanoate, and high DHT levels may cause acne, prostate issues, and hair loss.
9 citations,
July 2018 in “European journal of dermatology/EJD. European journal of dermatology” Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.
7 citations,
May 2012 in “International Journal of Andrology” The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.
27 citations,
February 2020 in “Journal of Cardiovascular Translational Research” Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.
11 citations,
November 2009 in “Sports Medicine” Irregular menstrual cycles in exercising women may be linked to energy deficiency or hormonal imbalances, requiring careful diagnosis for proper treatment.
2 citations,
September 2022 in “Asian Journal of Microbiology, Biotechnology & Environmental Sciences” Zinc is essential for plant growth and human health.
1 citations,
July 2020 in “Dermatology” Photobiomodulation helps reduce pain, lessen inflammation, heal wounds, and can be used in skin treatments. It also boosts hair growth in women with hair loss and may help fight microbes and prevent respiratory issues in COVID-19.