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Lifestyle changes improve metabolism and fertility in overweight PCOS patients; anti-obesity drugs show potential but need more research.

Some breast cancer chemotherapy can cause permanent hair loss.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

Toxic Shock Syndrome cases increased due to new factors, but decreased with public health measures and changes in tampon use.

Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

The transscrotal testosterone patch normalizes hormone levels in men with AIDS and weight loss but does not improve weight, body mass, or quality of life.

Scalp cooling can reduce chemotherapy-induced hair loss and should be available in all hospitals.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Celiac disease can cause skin problems that may get better with a gluten-free diet.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

The document concludes that more research is needed to understand how to treat muscle pain with drugs.

The conclusion is that genetic changes in the glucocorticoid receptor can lead to conditions affecting stress response, immunity, and metabolism, requiring personalized treatment.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

The VQ-Dermato is a reliable French questionnaire for measuring quality of life in chronic skin disorder patients.

Hormonal therapies are safe and effective for treating adult women's acne.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.