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Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.

Testosterone is crucial for development, growth, and various body functions in mammals.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Many adult women suffer from persistent or late-onset acne, and while various treatments exist, finding the right one can be challenging.

Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.

New treatments and diagnostic methods for various animal skin conditions showed promising results.

Raccoon dogs in Schleswig-Holstein, Germany, were found with sarcoptic mange, showing severe skin issues and potential for spreading the disease.

Researchers found two genes that may explain why some Casertana pigs don't have hair.

Mutations in the androgen receptor gene cause Androgen Insensitivity Syndrome, affecting sexual development.

The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.

Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.

New genes and pathways are important for testosterone production and male sexual development.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

Doctors used a special blood sampling technique to diagnose a woman's rare ovarian tumor that was producing male hormones.

Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.

Five new mutations in the androgen receptor gene were found, helping to understand androgen insensitivity syndrome better.

Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.

Lamins are vital for cell survival, organ development, and preventing premature aging.

The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

Human head hair proteins can be typed into eight distinct patterns, useful for genetic and forensic investigations.

Keratin proteins are consistent across different hair types from the same person.

The document suggests a possible link between FAM111B gene mutations and increased cancer risk, particularly pancreatic cancer.

AE can have varied symptoms and genetic causes, but zinc therapy helps.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

Quantifying hair shape is better than using racial categories for understanding hair characteristics.

Differences in growth factors in platelet-rich plasma therapy for hair loss can vary between patients and can be influenced by the devices used, possibly leading to inconsistent results.

Testosterone significantly affects urination differences between male and female mice.

MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.