Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the cellular and molecular changes involved in cutaneous wound re-epithelialization and EMT, highlighting their similarities and differences, but reports no new clinical results.

This review discusses the effects of hormonal changes on hair follicles, concluding that hormones like androgens and estradiol significantly influence hair growth and cycle, while the roles of other hormones are still being researched.

This article discusses the phases and histological features of alopecia areata and reports no new clinical findings; the authors emphasize recognizing these phases for accurate diagnosis.

This study observed that both ritlecitinib and brepocitinib improved scalp biomarkers in patients with alopecia areata, with associations to hair regrowth seen in this phase 2a trial.

This review discusses the phases of the human hair cycle, the factors affecting telogen effluvium, and the need for investigation if persistent hair shedding occurs, but reports no new clinical results.

This study observed that mink dermal collagen fibrils undergo structural changes during the hair cycle, with increased fiber thickness and bundle density as minks grow.

This source discusses a Phase 2 trial by Hu et al. that evaluated the efficacy of topical GT20029 compared to a placebo, though the abstract does not provide specific results.

This study observed distinct changes in the ultrastructure of Hexi cashmere goat hair follicles throughout the year, highlighting stages with specific cellular and structural characteristics.

This study observed structural and molecular changes in Ganxi goat skin that adapt to hot and humid climates and suggested that GSDMA might play a role in hair follicle regulation and skin homeostasis, though further research is needed to confirm its function in environmental adaptation.

This article proposes five mechanisms for telogen effluvium based on changes in the follicular cycle, which are supported by clinical findings, highlighting the condition's diverse causes.

This review discusses the formation and maintenance of hair follicles through dynamic cellular changes and signaling pathways, presenting a comprehensive overview but providing no new experimental findings.

In this study, yeast fermentation of Platycladus orientalis leaves was shown to enhance hair growth-promoting properties by affecting cell cycle phases in human dermal papilla cells, increasing growth factor VEGF, reducing inflammatory factor TGF-β1, and altering the expression of Wnt/β-catenin pathway-related genes.

In this study, distinct metabolic profiles were identified in women with PCOS, suggesting potential biomarkers for diagnosis based on changes in lipid and androgen metabolism.

This study found that among Japanese women with diffuse hair loss, decreased hair density without changes in vellus hair was the most common and distinct pattern observed, highlighting differences from previous observations in other populations.

This review discusses the cutaneous side effects of chemotherapy, noting that they frequently involve changes to skin, hair, and nails, and reports no new results.

This study found that low-level laser treatment may promote hair regrowth in mice by activating the Wnt10b/ß-catenin pathway and inducing the anagen phase of hair follicles.

This study observed that children with multisystem inflammatory syndrome associated with COVID-19 exhibited physical intolerance and fatigue shortly after the acute phase, but significant improvements in exercise capacity, laboratory markers, and cardiac health were reported by six months post-discharge.

The researchers reported that PPARβ/δ may influence the yak hair follicle cycle by modulating lipid metabolism in dermal papilla cells, with varying expression during different hair growth phases, affecting both lipid content and cell proliferation.

This study found that in mutant NRAS melanoma, MEK inhibitors led to increased AKT signaling and reduced MIG6, a change that may enhance cell migration and invasiveness.

In this review, researchers explored thermo-responsive polymers and their applications in nanomedicine, highlighting their role in targeted drug delivery, gene therapy, and imaging, enabled by their temperature-sensitive phase transitions to ensure localized therapeutic action and minimize damage to healthy tissues.

In this study, ethanamizuril was found to cause alopecia, biochemical changes, and organ damage at higher doses in rats, with a no-observed-adverse-effect level of 20 mg/kg over 30 days.

The researchers suggest that inflammation could be a key mechanism in the development of long COVID, potentially causing symptoms that emerge months after the acute phase of the disease resolves.

This study highlights that the skin can serve as a marker for systemic health during COVID-19 by showing symptoms like rashes and pigmentary changes, while also emphasizing dermatologists' key role in diagnosing COVID-induced and vaccine-related skin issues to enhance patient care and address vaccine hesitancy.

In this study, researchers observed that in mice, as they age beyond 200 days, unusual curved hair follicles and increased white hairs emerge, indicating stem cell-related changes in keratinocyte and melanocyte characteristics, providing insights into hair aging processes.

Diphencyprone initially increases mouse hair growth, then slows it, possibly due to changes in specific protein levels.

This study found that human hair surfaces exhibit nonhomogeneous wettability, potentially influenced by daily rhythms and even monthly changes possibly linked to the menstrual cycle.

This study found that chronic UVR exposure in mice and humans leads to a permanent loss of papillary fibroblasts in the upper dermis, which is associated with changes in the extracellular matrix.

Apoptosis may play a role in feather and hair development, SF-36 is better for mental health in skin patients, a psoriasis gene is found in Caucasians, eosinophils might not be crucial for some skin allergies, and changes in atopic dermatitis could increase skin sensitivity.

This study reported distinct expression patterns and potential functions of lncRNAs during the hair follicle cycle in yaks, suggesting insights into lncRNA roles and conservation between yak and cashmere goat.

This study found that mice lacking the vitamin D receptor showed disrupted hair follicle cycling and balance between cell proliferation and differentiation, highlighting VDR's role in hair cycling regulation.