research Novel Janus Kinase Inhibitors in the Treatment of Dermatologic Conditions
JAK inhibitors show promise for treating various skin diseases.
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research The Role of Benign Prostatic Hyperplasia Treatments in Ejaculatory Dysfunction
Treatments for enlarged prostate can cause problems with ejaculation, and less invasive options might preserve sexual function better.
research Baricitinib Safety for Events of Special Interest in Populations at Risk: Analysis from Randomised Trial Data Across Rheumatologic and Dermatologic Indications
Baricitinib, a drug for rheumatoid arthritis, atopic dermatitis, and alopecia areata, is generally safe with low risk of major side effects, even in patients with risk factors. It's also effective in promoting hair regrowth in alopecia areata patients.
research Dupilumab: A Review of Present Indications and Off-Label Uses
Dupilumab is being tested for many new skin, respiratory, and gastrointestinal conditions.
research An Open-Label Pilot Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.
research Efficacy and Safety of Oral Alitretinoin in Chronic Hand Eczema and Palmoplantar Pustulosis
Oral alitretinoin is effective for certain types of chronic hand eczema, with mild side effects.
research Young Patients Using Finasteride Exhibit Risk of Suicidality
Finasteride use in young people may increase risk of suicidal thoughts and mental health issues.
research The British Society for Rheumatology Guideline for the Management of Systemic Lupus Erythematosus in Adults
The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.
research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
research Janus Kinase Inhibitors For Alopecia Areata
JAK inhibitors effectively improve hair regrowth in alopecia areata with an acceptable safety profile.
research Endocrine Treatment of Benign Prostatic Hypertrophy: Current Concepts
New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.
research Hormone Receptor Positive, HER2 Negative Metastatic Breast Cancer: Impact of CDK4/6 Inhibitors on the Current Treatment Paradigm
CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.
research Impact of Clinical Response on Different Approved Doses in Japan and the United States
Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.
research Current Systemic Treatment Strategies for Hidradenitis Suppurativa
Adalimumab is the most effective treatment for severe hidradenitis suppurativa, but more research is needed to improve treatment options.
research Genital Dermatology and Hidradenitis Suppurativa
A new diagnostic tool for Vulvovaginal Lichen Planus is highly accurate, and updated treatments for various skin conditions, including melanoma and Hidradenitis Suppurativa, were discussed.
research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
research Automated Machine Learning Analysis of Patients With Chronic Skin Disease Using a Medical Smartphone App: Retrospective Study
Machine learning can predict symptoms and quality of life in chronic skin disease patients using smartphone app data, and shows that app use varies with patient characteristics.
research The Itchy Scalp: An Overview of Scalp Pruritus and Its Management
Up to half of people experience itchy scalp, often due to skin conditions like seborrheic dermatitis or psoriasis, and treatments vary based on the specific cause.
research Janus Kinase Inhibitors in Dermatology: A Systematic Review
JAK inhibitors help with skin conditions but need more research on dosing and safety.
research Under Development JAK Inhibitors for Dermatologic Diseases
New JAK inhibitor drugs show promise for treating skin diseases but need more research on safety and effectiveness.
research Impact of Alpha Blockers, 5-Alpha Reductase Inhibitors, and Combination Therapy on Sexual Function
Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.
research Inhibition of T-Cell Activity in Alopecia Areata: Recent Developments and New Directions
New treatments targeting T-cell pathways are needed for better alopecia areata management.
research Management of Hidradenitis Suppurativa
Treating hidradenitis suppurativa needs long-term care and teamwork among doctors, but there's a lack of strong guidance on how to do it.
research Treatments for Moderate-to-Severe Alopecia Areata: A Systematic Narrative Review
Some treatments for severe hair loss work but often have side effects, with baricitinib showing the most promise.
research Review on Alopecia Areata in the Middle East and Africa: Landscape and Unmet Needs
The Middle East and Africa need better data, treatment consensus, and support for Alopecia Areata.
research Parkinson's Disease and Skin Disorders: Non-Iatrogenic and Iatrogenic Connections
Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.
research Alopecia After Injection of ATX-101 for Reduction of Submental Fat
ATX-101 injections can cause hair loss.
research Surgical Approaches for Repigmenting Vitiligo 2.0
Assessing CD8+ T cell levels before surgery may improve vitiligo treatment outcomes.
research 9-cis-Retinoic Acid Capsules in the Treatment of AIDS-Related Kaposi Sarcoma
9-cis-retinoic acid showed some effectiveness in treating AIDS-related Kaposi sarcoma but had significant side effects at higher doses.
research The Relative Efficacy of Monotherapy With Janus Kinase Inhibitors, Dupilumab and Apremilast in Adults With Alopecia Areata: Network Meta-Analyses of Clinical Trials
JAK inhibitors are more effective and safer for treating alopecia areata than dupilumab and apremilast.