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New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

Second-generation antipsychotics offer no significant benefit over first-generation ones for schizophrenia.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Human skin can make serotonin and melatonin, which help protect and maintain it.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Diazoxide, minoxidil sulphate, and cromakalim relax rat blood vessels by opening K+ channels, with some differences in their actions.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.

A team approach is crucial for managing PCOS, with dermatologists playing a key role.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Allergic reactions to blood thinners are rare but can be serious, requiring careful management and alternative treatments.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.

Lovastatin doesn't improve lower urinary tract symptoms treatment.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

New treatments for enlarged prostate are being developed, some of which may be more effective than current medications.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

A yeast-based test can detect the steroid methyltestosterone in urine longer than traditional methods.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Synthetic cannabinoid addiction can cause skin problems like acne and hair loss.