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PDRN helps repair tissue and improve wound healing with a high safety profile.

New treatments for male hypogonadism are effective and should be personalized.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Hair color loss can indicate the effectiveness of a drug targeting the KIT protein in mice and humans.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Alisertib was found to be an effective and tolerable treatment for children with recurrent brain tumors.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Microneedle technology has improved drug delivery and patient comfort but needs more research for broader use.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Cyclosporin is effective for treating skin conditions in small animals, but requires careful dosing and monitoring for side effects.

Minoxidil, propranolol, and furosemide effectively control severe hypertension, but may cause sodium retention.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

New finasteride solution effectively reduces baldness-causing hormone, potentially with fewer side effects.

Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Some plants used in traditional medicine may help treat cancer because they contain proteins that can inactivate ribosomes.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Minoxidil can harm dog's heart.