October 2025 in “Scientific Reports” This study found that the extracts of Serenoa repens, when evaluated through chemical, biological, and in silico methods, demonstrated anti-inflammatory, pro-apoptotic, and anti-androgenic activities against prostate cancer cell lines, suggesting potential therapeutic benefits and directing future pharmaceutical development.
25 citations
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January 2024 in “Journal of Lipids” This review reports that cubosomes, used as drug nanocarriers in topical treatments, offer potential benefits for managing skin and eye diseases by improving bioadhesion, retention, and sustained release compared to conventional formulations, but also face manufacturing and biological challenges for effective clinical outcomes.
24 citations
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September 1995 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This article discusses the combination of mechanical hair removal and medication use for hirsutism improvement, noting that no drugs are approved for this condition in North America, and calls for well-designed comparative studies.
21 citations
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January 2008 in “Talanta” New, cheaper method measures finasteride in tablets accurately and quickly.
20 citations
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August 2017 in “Drug testing and analysis” This study used micro-segmental hair analysis to identify the day of drug intake and suggested differing uptake mechanisms for co-administered drugs based on their properties.
17 citations
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October 2012 in “Dermatologic clinics” This article discusses diagnostic and treatment options for excessive hair growth in women, noting a need for holistic approaches to address associated psychological issues, but it does not present new clinical findings.
12 citations
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September 2021 in “Journal of molecular structure” In this study, researchers created a new molecular salt from minoxidil and 2,4-dihydroxybenzoic acid, finding it superior to raw minoxidil for promoting hair growth in a mouse model, suggesting it may be a promising candidate for treating hair loss.
11 citations
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March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” This study found that young host mice rejuvenated aged hair follicles after transplantation, while aged host mice did not support hair growth from transplanted follicles.
2 citations
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January 2016 in “UvA-DARE (University of Amsterdam)” This review explores the unclear rationale behind excluding medical treatment methods from patentability and the complexities of allowing medical indication patents, offering potential solutions but reporting no new results.
2 citations
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November 2015 in “Journal of Investigative Dermatology Symposium Proceedings” This article discusses the creation of Alopecia Areata Uniform Protocols by the National Alopecia Areata Foundation to standardize clinical trials for alopecia areata treatments and reports no new results.
2 citations
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March 2015 in “Toxicology and Environmental Health Sciences” This study found that rice bran supercritical CO₂ extract was classified as a non-irritant for ocular use but a moderate irritant for dermal use in rabbits and guinea pigs.
2 citations
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November 2014 in “Pharmaceutical Patent Analyst” This article provides an update on several international patent cases, including a decision that could change Japan's patent term extension practice, but it reports no new research results.
1 citations
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August 2023 in “International journal of pharmacy & integrated health sciences” This review discusses various bioactive elements in cosmeceuticals, highlighting their potential benefits, such as anti-aging effects and skin tone improvement, while noting the growing demand due to safety concerns and expanding market opportunities.
1 citations
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July 2023 in “Foods” This review explores the diverse biotechnological uses of mushrooms, emphasizing their potential to enhance food, energy, and water security, and their alignment with the UN's sustainable development goals.
1 citations
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June 2022 in “International Journal of Health Sciences (IJHS) (En línea)” This review discusses the importance of herbal oils for hair health, emphasizing their benefits over synthetic products due to fewer potential side effects, and reports no new experimental findings.
1 citations
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December 2019 in “Formuly farmacii” This article reviews the complex etiology of alopecia and emphasizes the need for detailed pathogenesis studies in animal models to develop effective personalized treatments, without presenting new experimental data.
1 citations
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January 2017 in “Springer eBooks” This chapter reviews the hair follicle's role in drug and chemical penetration through the skin but does not present new experimental findings.
1 citations
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September 2024 in “International Journal of Pharmaceutical Sciences Review and Research” This review discusses various oils used in herbal cosmetics for skin and hair care applications but reports no new clinical findings.
March 2025 in “Regenerative Therapy” This study suggests that SACM may enhance hair growth more effectively than non-treated ACM, highlighting the potential of S. maxima as a promising agent for use in pharmaceutical and cosmeceutical industries.
December 2022 in “Korean journal of medicinal crop science/Han-gug yagyong jagmul hag-hoeji” This study found that polysaccharide extracts from ginseng, green tea, shiitake, and aloe vera effectively protected human follicle dermal papilla and keratinocyte cells by promoting cell proliferation or inhibiting apoptosis, suggesting potential for these extracts as ingredients in cosmetics or pharmaceuticals to prevent hair loss.
May 2026 in “Jurnal Riset Kefarmasian Indonesia” This study measured caffeine content in ethanolic extracts of robusta coffee beans, finding 221.58 mg of caffeine per gram of extract, which aligns with known levels for Coffea canephora.
May 2026 in “Revista fisio&terapia.” This narrative literature review found that combined therapies such as minoxidil, microneedling, and platelet-rich plasma are more effective than isolated treatments for androgenetic alopecia, improving hair density and quality. The study highlights the role of pharmaceutical intervention in enhancing treatment adherence and clinical outcomes.
March 2026 in “Mini-Reviews in Medicinal Chemistry” This review reports that pharmacogenomic variations in the SULT1A1 enzyme significantly influence the response to minoxidil treatment for alopecia, suggesting personalized therapeutic strategies could improve efficacy while emerging pharmaceutical technologies aim to optimize oral minoxidil's absorption and minimize side effects.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review article summarizes the phytochemistry, preparation methods, applications, and potential therapeutic benefits of fenugreek-based hair oil, suggesting its use as a natural remedy for hair growth, scalp health, and conditioning, while also noting its safety and future potential in cosmetic and pharmaceutical formulations.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review outlines the phytochemistry, preparation methods, and potential therapeutic benefits of fenugreek-based hair oil, suggesting its use for hair growth and scalp health, while emphasizing its safety and future prospects in cosmetics and pharmaceuticals.
January 2026 in “National Journal of Pharmaceutical Sciences” This study developed and validated a Gas Chromatography-Flame Ionization Detection method for assessing minoxidil, which shows good precision, accuracy, and specificity for quality control and pharmacokinetic studies.
October 2025 in “Lithuanian University of Health Sciences” This study documented 81 plant species used traditionally in Lithuania's Šiauliai District for treating skin diseases and cosmetic purposes, highlighting the continued relevance of plant-based remedies and the market demand for natural products.
August 2025 in “Aesthetic Plastic Surgery” This review explores the mechanisms, current products, challenges, and innovative approaches related to cosmetics for hair loss prevention and growth promotion, emphasizing the need for multidisciplinary cooperation to enhance product development and market success.
May 2025 in “REVISTA DA ASSOCIAÇÂO DE FARMÁCIAS VIVAS” This study introduced an innovative antioxidant serum for skin care, using a lipid active from Rana catesbeiana Shaw, and validated its rejuvenating potential through physical-chemical and microbiological tests that ensured its antioxidant effectiveness, microbiological safety, and formulation stability.
January 2025 in “International Journal of Pharmaceutical Research and Development” This source highlights the preference for herbal-based products over chemical treatments for managing alopecia and explores their potential in hair treatment and regrowth.