research Effect of Indole-Based Derivatives on Rats with Polycystic Ovary Syndrome
Indole-based compounds improved ovarian health in rats with PCOS, with L-Tryptophan and Tryptophol being most effective.
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research Development of a Non-Parametric Population Pharmacokinetics Model and Bayesian Estimator for Tacrolimus in Tunisian Renal Transplant Patients
The model and estimator can predict drug exposure in kidney transplant patients well.
research Trichotillomania: Chronic Disorder Characterized by Compulsive Hair Pulling
Trichotillomania is a chronic hair-pulling disorder, more common in females, treated with therapy and sometimes medication.
research Role of Sdf1-Cxcr4 Signaling in Mouse Appendage Regeneration
Mice without the p21 gene can fully regenerate injured ears due to reduced Sdf1 increase and leukocyte recruitment, suggesting new ways to induce tissue regeneration in mammals.
research Childhood Trichotillomania: Diagnostic Algorithm and Systematic Problem-Solving Management Using the 5W1H (Kipling’s Principle)
The conclusion is that using the 5W1H method can improve diagnosis and management of childhood hair-pulling disorder.
research Hair Today, Gone Tomorrow: Potential of Tofacitinib and Ruxolitinib in Treating Hair Loss
Two drugs, tofacitinib and ruxolitinib, may help regrow hair by activating hair follicles.
research Trichotillomania: Hair Pulling Disorder
Habit reversal training effectively treats hair-pulling disorder in both adults and children.
research Rely on Clinical Experience to Guide Treatment Selection for Primary Cicatricial Alopecias
Doctors use their experience to choose treatments for scarring hair loss because it's hard to diagnose and treat.
research Wound Healing
Wound healing is complex and requires more research to enhance treatment methods.
research Hair Biology and Nutritional Influences
Eating a balanced diet with the right vitamins and minerals is important for healthy hair, but too many supplements can be harmful.
research Aging of Hair and Its Treatment
Hair ages by graying and thinning, treatable with medications, transplants, or hair dye.
research Court of Appeal Can Overrule Itself to Follow the EPO: UK Adopts EPO Stance on Second Medical Use Claims
The UK Court of Appeal ruled that new dosing regimens for drugs can be patented, aligning with the European Patent Office's approach.
research Aesthetics and Cosmetic Surgery for Darker Skin Types
The book provides a guide to cosmetic surgery for people with darker skin, covering various treatments and addressing their unique skin characteristics.
research Polycystic Ovarian Syndrome and Obstructive Sleep Apnea
Women with PCOS are much more likely to have sleep problems and should be checked for them.
research Slow Progress in Prostate Cancer
Finasteride reduces prostate cancer risk but may increase high-grade tumors; new drugs and better diagnosis are in development, but funding and industry commitment are challenges.
research Effect of Ginseng Extract on the Follicular Growth of C57BL/6J Vibrissa
Ginseng extract can enhance hair growth at certain concentrations.
research Contents
Better understanding of hair patterns and advanced techniques are crucial for improving hair restoration and removal outcomes.
research Error Correction
The document corrects a mistake by stating that pimecrolimus, not tacrolimus, is the drug that concentrates in the skin.
research Reply
Dr. Jorizzo questions the long-term benefits of minoxidil and tretinoin, while Dr. Olsen defends their effectiveness and stresses the need for public education on these treatments.
research Chemotaxis in Psoriasis
Psoriasis patients have immune cells that respond more strongly to signals and stimuli due to an intrinsic cellular defect.
research Industry News
The U.S. soybean industry wanted government help due to foreign competition, while the jojoba industry was growing and expected to stabilize.
research Approaches for Estimating the Clinical Starting Dose of New Dosage Forms: An Example of a Long-Acting Injectable Formulation of Finasteride
The best starting dose for a new finasteride injection is 16.80 mg.
research In Young Patients, The Use Of Finasteride Could Be Associated With Increased Risk Of Anxiety, Depression, And Suicide-Related Adverse Events
Young patients using finasteride may have higher risks of anxiety, depression, and suicidal thoughts.
research Development of Stable and Simple Finasteride 333-μg/mL Suspensions That Minimize Occupational Exposure
A stable and simple finasteride suspension was developed that retains over 94.3% of its concentration for up to 90 days and doesn't significantly increase occupational exposure, but safety measures are still advised.
research Author’s Reply to the Comment on: The Effect of Intradermal Botulinum Toxin on Androgenetic Alopecia and Its Possible Mechanism
Botulinum toxin affects hair follicles, inhibiting TGF-B1 secretion; more research ongoing.
research Letter to the Editor: Androgenetic Alopecia; Drug Safety and Therapeutic Strategies
Dutasteride is a safe and effective treatment for hair loss.
research Combination of Finasteride and Tamsulosin in the Treatment of Male Lower Urinary Tract Symptoms: What Are Patients Thinking?
Patients follow treatment well, but many change medicines; good information helps compliance.
research Lgr5 Marks Cycling, Yet Long-Lived, Hair Follicle Stem Cells
Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.
research Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis
VEGF helps hair grow and determines follicle size by increasing blood vessel growth.
research Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling
Fat-related cells are important for initiating hair growth.