May 2025 in “The Journal of Rheumatology” This study reports that even minimal improvements in SLE-related fatigue and skin symptoms are meaningful to patients, supporting the content validity of the FACIT-Fatigue scale for measuring these effects.
September 2022 in “Journal of Investigative Dermatology” This study found that the Severity of Alopecia Tool score does not predict the quality of life in patients with alopecia areata, suggesting patient-reported outcomes better reflect the impact on life quality.
March 2024 in “Journal of Microbiology and Biotechnology” This study suggests that phloroglucinol may enhance anagen signaling and reduce oxidative stress-induced damage in human dermal papilla cells, offering a potential therapy for hair loss.
26 citations
,
October 2017 in “Clinical Reviews in Allergy & Immunology” This review explores skin manifestations associated with autoimmune liver diseases and highlights known and probable links, such as vitiligo's strong association with autoimmune hepatitis.
16 citations
,
December 2016 in “Skin appendage disorders” This study analyzed patch test results to identify allergens causing scalp contact dermatitis, finding nickel, cobalt, and balsam of Peru among the most common in the patient population.
53 citations
,
September 2020 in “Stem Cell Research & Therapy” This review discusses strategies to enhance mesenchymal stem cell therapy effectiveness but reports no new clinical results; it highlights the need for improved consistency and efficacy in MSC-based treatments.
22 citations
,
November 2021 in “Dermatology and Therapy” This study found that the Alopecia Areata Patient Priority Outcomes questionnaire is a reliable and valid tool for measuring the severity and impact of hair loss in individuals with alopecia areata.
20 citations
,
March 2013 in “Journal of Lipid Research” This study examined the structural and biochemical mechanisms of human lipocalin prostaglandin D synthase, detailing substrate and product binding processes at the catalytic site and suggesting potential for drug delivery targeting hydrophobic molecules.
16 citations
,
June 2017 in “PLoS ONE” This small study reports that a 6-group geometric classification method is more reliable for classifying human hair curl, although a digital system could further reduce errors.
January 2026 in “Military Medicine” This article discusses how lipopolysaccharide (LPS) from gram-negative bacteria activates platelets and affects vascular responses, emphasizing the role of reactive oxygen species (ROS) in these processes, without reporting new experimental findings.
March 2025 in “HAL (Le Centre pour la Communication Scientifique Directe)” This thesis investigates the underlying mechanisms and treatment options for androgenetic alopecia, highlighting the molecular roles of androgens and genetic predispositions, and evaluates current and emerging therapies, such as PROTACs and Janus Kinase inhibitors, to enhance patient management.
This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.
51 citations
,
October 2002 in “British Journal of Dermatology” Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
11 citations
,
August 2010 in “Developmental neurobiology” This study suggests that Ptprq in the hair bundles may exist as multiple isoforms that are differentially expressed throughout development and affect the organization of stereocilia in the chick inner ear.
4 citations
,
June 2002 in “Clinical and experimental dermatology” This review discusses current treatments and management strategies for hidradenitis suppurativa, noting the mixed effectiveness of various therapies, including surgery, antibiotics, and hormonal treatments, but reports no new clinical findings.
2 citations
,
February 2018 in “InTech eBooks” This article discusses adverse immune-mediated skin reactions associated with TNF-alpha inhibitors, highlighting paradoxical reactions such as psoriasis that occur despite being treated with medications intended to alleviate the condition.
July 2011 in “British Journal of Dermatology” Dermatologists give better information on pathology forms, hypersensitivity vasculitis is a common skin issue, misdiagnoses can occur, and various skin conditions are linked to loss of elastin or genetic factors.
January 2009 in “Springer eBooks” The document concludes that managing skin conditions during pregnancy is important and requires specialized care.
This study found changes in the PGI2 pathway, especially in gene and protein expression, in diabetic mice, but did not observe PGI2-dependent vasomotor dysfunction.
November 2024 in “Journal of Investigative Dermatology” Polygenic Score can help predict severe psoriasis and psoriatic arthritis.
3 citations
,
January 2005 in “Biological & Pharmaceutical Bulletin” This study reports that the peptide GPIGS, found in Bacillus sp. M18 conditioned medium, may promote hair growth through the PI-3K/Akt pathway and accelerate hair regrowth in mice.
April 2023 in “Journal of Investigative Dermatology” In this study, the KPAI and KP-IGA scoring systems for assessing keratosis pilaris showed excellent interrater and intrarater reliability, offering standardized measures for clinical and research use.
51 citations
,
May 2004 in “American journal of ophthalmology” This study reports that poliosis can be an adverse effect of topical prostaglandin F2α analog therapy in patients treated for primary open angle glaucoma.
205 citations
,
March 2012 in “Science Translational Medicine” PGD2 stops hair growth and is higher in bald men with AGA.
This article explores the potential applications of polyglutamic acid in cosmetics, discussing its benefits for skincare and haircare, but reports no new experimental results.
3 citations
,
September 2025 in “Neural Regeneration Research” This review discusses the roles of prostaglandins in the nervous system and their therapeutic potential for neurological diseases, noting their complex interactions with immune cells and signaling pathways.
1 citations
,
January 2016 in “Journal of gastrointestinal & digestive system” The researchers reported that the SAGI PGP procedure resulted in excess weight loss of over 90% in the first year and normalized blood sugar levels without medication among diabetic patients by the first month post-operation.
September 2023 in “Journal of the American Academy of Dermatology” This study evaluated the effect of guselkumab on moderate to severe plaque psoriasis and found that median PASI improvements increased from around 60% at week 4 to over 90% by week 12 of treatment across multiple clinical trials.
7 citations
,
April 2024 in “Skin Research and Technology” This study found that ChatGPT provided fairly accurate answers to common psoriasis-related questions, as rated by medical experts, although it doesn't fully replace professional medical judgment or diagnosis.
2 citations
,
September 2023 in “PubMed” The studies reviewed found favorable treatment outcomes for hypopigmented scars using PGF2α agonists with no adverse events reported. However, the authors highlight the need for larger randomized controlled trials to better understand their effectiveness and long-term safety.