40 citations,
November 2013 in “European journal of endocrinology” Effective hirsutism treatment for women with PCOS should be personalized and may include lifestyle changes and medication.
1 citations,
January 2010 in “Serbian Journal of Dermatology and Venereology” The document concludes that effective acne treatment requires a personalized combination of therapies and long-term commitment, with retinoids being important for maintenance.
77 citations,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
466 citations,
June 2009 in “Experimental dermatology” We now understand more about what causes acne and this could lead to better, more personalized treatments.
15 citations,
April 2008 in “Headache” People with migraines often have mental health conditions, and treatment should be personalized to address both issues safely.
4 citations,
June 2015 in “Journal of Genetics/Journal of genetics” Genetic differences within ethnic groups may affect prostate cancer treatment effectiveness.
2 citations,
March 2022 in “Journal of Personalized Medicine” Personalized medicine is important for treating skin disorders, with new treatments and connections to hormones and genetics being explored.
24 citations,
January 2017 in “Dermatology online journal” Hormonal therapies might help treat hidradenitis suppurativa, but treatment is complex and personalized.
21 citations,
January 2021 in “Frontiers in Pharmacology” The document reviewed the role of thiopurines in treating inflammatory bowel diseases (IBD), emphasizing their effectiveness in maintaining remission and the importance of genetic testing to minimize adverse effects. Thiopurines, such as azathioprine and 6-mercaptopurine, were effective but posed risks like leukopenia and alopecia, particularly in individuals with NUDT15 polymorphisms. Combination therapy with biological agents showed improved outcomes. The review highlighted the need for personalized medicine approaches, including pharmacogenetic testing, to optimize treatment and minimize side effects, and called for further research to balance the benefits and risks of thiopurines.
September 2022 in “Journal of The American Academy of Dermatology” The study investigates the impact of skin type on the efficacy of low light laser therapy for treating androgenic alopecia. A comprehensive literature search of the MEDLINE database revealed that only 8 out of 21 studies included Fitzpatrick skin types I-IV, while 13 studies did not mention skin type or color. None of the studies addressed effects on Fitzpatrick skin types V-VI. Among the 8 studies, only 3 statistically analyzed the effect of skin type on laser efficacy, with 2 showing no effect and 1 indicating a significant positive effect for darker skin types. The conclusion highlights a lack of sufficient data to determine the impact of skin type on laser-induced hair growth, emphasizing the need for more research, especially on black or brown skin colors, to develop personalized laser therapy settings.
4 citations,
August 2021 in “Pediatrics in review” DSDs are birth conditions causing unusual sex development, managed with personalized care and sometimes surgery, but still lack a standard treatment approach.
Individualized treatment plans, including lifestyle changes and specific medications, are crucial for managing PCOS in adolescents.
September 2022 in “PubMed” Personalized homeopathy medicine, along with lifestyle changes, can effectively treat Polycystic Ovarian Syndrome.
57 citations,
February 2016 in “Dermatologic surgery” Different reasons for large pores mean treatments need to be personalized.
37 citations,
December 2021 in “Cells” Alopecia areata severity and treatment response are linked to specific cytokine levels.
September 2022 in “Women's healthcare” PCOS is managed by lifestyle changes and personalized medication to improve symptoms and fertility.
February 2007 in “Lancet Oncology” Using a single PSA level to decide on a prostate biopsy is not effective; a more personalized approach considering various factors is recommended.
February 2021 in “Journal of pharmaceutical and biological sciences” No cure exists for alopecia areata, and treatments are personalized.
391 citations,
November 2015 in “Journal of Clinical Lipidology” The guidelines suggest lifestyle changes, diet adjustments, and personalized medication to manage dyslipidemia and reduce heart disease risk.
27 citations,
January 2015 in “Current problems in dermatology” The document concludes that primary scarring alopecias cause permanent hair loss, have unpredictable outcomes, and lack definitive treatments, requiring personalized care.
13 citations,
June 2019 in “Medicina Clínica (english Edition)” PCOS is a common hormonal disorder in women that can affect skin, fertility, and metabolism, and treatment is tailored to individual needs.
June 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new risk spots for early hair loss were found, which also link to Parkinson's disease and lower fertility. Two genes, FOXA2 and HDAC4, could be new treatment targets. Hair loss might also be connected to heart disease, metabolic syndrome, and prostate cancer.
May 2023 in “Vestnik dermatologii i venerologii” Early-stage male pattern baldness shows two types of hair loss: one on the top of the head linked to hormonal changes, and another at the back of the head. The top hair loss responds well to specific treatment, while the back hair loss does not.
21 citations,
May 2021 in “Patient education and counseling” Managing PCOS is hard because it varies a lot, treatments are limited, and there's a lot of false information online.
11 citations,
January 2011 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” Adolescents and young adults with Prader-Willi syndrome show a range of sexual interests and behaviors.
4 citations,
August 2023 in “Materials” New synthetic polymers help improve skin wound healing and can be enhanced by adding natural materials and medicines.
January 2013 in “Dermatology” The ILDS Newsletter reported on efforts to support albinism patients in Tanzania and dermatological conferences.
February 2024 in “Archives of Dermatological Research” Most patients know about minoxidil for hair loss, but concerns about its use and effectiveness affect their decision to use it.
16 citations,
June 2018 in “JAAD case reports” A JAK inhibitor improved both severe hair loss and chronic skin disease in one patient.
November 2023 in “Journal of Investigative Dermatology” This study analyzed scalp microbiota in 27 alopecia areata (AA) patients and 4 healthy controls, revealing an altered ratio of gram-positive to gram-negative bacteria in AA patients. After 52 weeks of treatment with JAK inhibitors (ritlecitinib or deuruxolitinib), most microbiota variations were restored, except for Proteobacteriota. These changes were consistent regardless of patient demographics or disease severity. The findings highlight the potential impact of JAK inhibitors on the skin microbiome and suggest new avenues for personalized AA treatments.