Therapeutic Options To Refractory Alopecia Areata

    Alejandra Jeraldine González Barajas, Paola Chávez Contreras
    TLDR Treating stubborn hair loss involves both medical and emotional support options.
    The document "Therapeutic Options to Refractory Alopecia Areata" reviews various treatments for alopecia areata, focusing on immune and inflammatory indicators, patient experiences, and the efficacy of different medications. Key treatments discussed include JAK inhibitors, such as ruxolitinib, which have shown promise in inducing hair regrowth in patients with moderate-to-severe alopecia areata. The review also covers the safety and effectiveness of other therapies like cyclosporine, minoxidil, spironolactone, and azathioprine. Additionally, it highlights the importance of understanding patient experiences and the need for personalized treatment approaches.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  827 upvotes 5 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Do hair follicles dies or are dormant ?

      in Finasteride/Dutasteride  92 upvotes 1 month ago
      Hair follicles can be dormant and potentially revived with treatments like finasteride and minoxidil, but irreversible loss occurs if certain structures are destroyed. Early intervention is more effective, and additional methods like microneedling may help.

      community I am a dermatologist with a clinical interest in alopecia. AMA

      in Will treatment work for me? 2 years ago
      In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

      community Upcoming treatment ideas in the future

      in Research/Science  11 upvotes 2 months ago
      Exploring future hair loss treatments, including immunosuppressants for hair transplants and hair cloning, with a focus on leveraging research from other medical fields. Current treatments like finasteride and minoxidil are effective for most, but there's a call for more funding and innovation in the hair loss industry.

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