Design and Implementation of an Image Processing System and Mathematical Optimization Algorithms for Human Hair Follicle Transplantation Using the FUE Technique

    June 2016
    Γεώργιος Ζώντος, Γεώργιος Ζώντος
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    TLDR The document concludes that the FOLLYSIS© system improves hair transplant processes and patient monitoring with high accuracy and less skin trauma.
    The document from 2016 detailed the creation of an image processing system and mathematical optimization algorithms for human hair follicle transplantation using the Follicular Unit Extraction (FUE) technique. The study introduced FOLLYSIS©, a system that allows doctors to archive patient data, use digital trichoscopy, design personalized treatment plans, record follow-ups, and quantify patient results. The system's accuracy was evaluated in 56 micro-photographs from different patients, achieving a sensitivity of 97.5% and an accuracy of 98.6%. It also demonstrated a significant reduction in skin trauma with the Vertical Extraction technique compared to Acute Extraction. FOLLYSIS© showed promise for diagnosing, treating, and monitoring patient progress, providing automated measurements of hair density changes and recording significant scalp sizes.
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      community Verteporfin and Microneedling

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      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.
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