19 citations
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September 2014 in “JAMA Dermatology” Eosinophilic infiltrate is not a reliable indicator for diagnosing chronic alopecia areata.
53 citations
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September 2011 Other common signs, not just the well-known immune cells around hair bulbs, are important for diagnosing hair loss from alopecia areata.
April 2020 in “International Journal of Dermatology” This study found that peribulbar lymphocytic infiltration can effectively differentiate between alopecia areata and androgenetic alopecia using T-cell infiltration patterns in skin tissue.
19 citations
,
December 2001 in “Dermatologic Therapy” This study reports that horizontal sections of scalp biopsies improve the diagnosis of alopecia areata, especially when characteristic inflammatory infiltrates are missing.
1 citations
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September 2021 in “Journal of The American Academy of Dermatology” This study observed that inflammation in androgenetic alopecia samples was similar to alopecia areata controls, but infundibular and isthmic inflammation were significantly more common in androgenetic alopecia cases.
January 2023 in “Journal of Cutaneous Pathology” This study found that histopathologic features such as a catagen/telogen shift, melanin in fibrous tracts, and small dystrophic follicles can help differentiate alopecia areata from pattern hair loss in the absence of peribulbar infiltrates.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” The study concluded that a 'Swiss cheese' pattern in hair follicles is a useful sign for diagnosing alopecia areata.
3 citations
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January 2019 in “Indian Journal of Dermatology” This study observed that transverse sectioning of scalp biopsies may aid in diagnosing different types of alopecia by revealing distinct histopathological features like follicle miniaturization and specific inflammatory patterns.
35 citations
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November 2010 in “Journal of Cutaneous Pathology” This study reported that dilated follicular infundibula are a highly useful histopathologic criterion for diagnosing alopecia areata, particularly during its recovery stage.
April 2012 in “Informa Healthcare eBooks” Syphilitic alopecia is a rare hair loss condition in secondary syphilis that looks similar to another condition but can be diagnosed with specific tests and responds to antibiotics.
25 citations
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October 1975 in “Journal of Cutaneous Pathology” This study found that in alopecia areata, hair bulbs are blocked in an early growth stage due to impaired metabolic function in the surrounding connective tissue, hindering hair growth.
16 citations
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February 1999 in “American Journal of Dermatopathology” This article describes a woman's case of slowly progressive nonscarring alopecia with unique biopsy findings, suggesting the need to reexamine similar cases currently classified as chronic diffuse alopecia areata.
2 citations
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March 2019 in “Journal of Dermatology” This report describes a rare case of alopecia areata coexisting with primary scarring alopecia, diagnosed through detailed trichoscopic investigation, highlighting the importance of comprehensive examination for accurate diagnosis.
January 2015 in “Indian Dermatology Online Journal” This diagnostic discussion reports that diffuse alopecia areata was identified in a patient with diffuse hair loss, based on specific histopathological features observed in a biopsy.
64 citations
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July 1997 in “Journal of The American Academy of Dermatology” This study found that eosinophils are a useful diagnostic feature for alopecia areata, especially when the typical "swarm of bees" lymphoid infiltrate is absent, helping differentiate it from trichotillomania.
9 citations
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January 2010 in “International Journal of Trichology” This study found that in Alopecia Areata, increased non-anagen terminal follicles and peribulbar lymphocytic infiltrate are consistent histological features, even in cases that have progressed to scarring.
8 citations
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June 2012 in “Australasian Journal of Dermatology” In this study, two patients with localized hair thinning showed histopathological signs typical of alopecia areata, responding to corticosteroid treatment similarly to classical cases.
6 citations
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March 1999 in “Seminars in Cutaneous Medicine and Surgery” This report presents four cases highlighting diagnostic challenges between specific types of alopecia, comparing their clinical and histopathologic features without providing new research findings.
January 2024 in “Pan African Medical Journal” This study aimed to document and compare the prevalence and characteristics of hair loss in patients with systemic lupus erythematosus, noting the differences in trichoscopic and histopathologic evaluations between those with and without alopecia. Results are not reported.
May 2023 in “Tạp chí Da liễu học Việt Nam” This study involving Vietnamese patients with alopecia areata found that histopathological examination is crucial for diagnosis, noting diverse features including peribulbar lymphocytic infiltration and varying hair follicle characteristics across disease stages, with eosinophils and necrosis observed in some cases.
43 citations
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May 2011 in “Dermatologic Therapy” This article discusses the phases and histological features of alopecia areata and reports no new clinical findings; the authors emphasize recognizing these phases for accurate diagnosis.
23 citations
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September 2019 in “Dermatology practical & conceptual” This study analyzed the features of alopecia areata incognita and diffuse alopecia areata, finding distinct patterns in hair loss regions and trichoscopic signs, and noted a benign course responsive to topical steroid therapy.
18 citations
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April 2010 in “Archives of Dermatology” This case report describes a patient with psoriasis and alopecia universalis where psoriasis plaques supported hair growth, suggesting cytokine interaction may influence competing immune responses.
10 citations
,
March 2014 in “International Journal of Dermatology” This report describes a case of postoperative pressure-induced alopecia in a 5-year-old girl following liver transplantation, suggesting that scalp dermatoscopy may help differentiate this condition from alopecia areata.
1 citations
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October 2013 in “BMJ” This case study reports a man with rapid hair thinning, whitening, and sparse beard, linked to an increased proportion of hair follicles in catagen or telogen phase and peribulbar lymphocytic infiltrate.
January 2026 in “International Research Journal of Modernization in Engineering Technology and Science” This review outlines the existing understanding of alopecia areata, detailing its autoimmune nature, clinical presentation, histology, and management strategies, with corticosteroids highlighted as the most popular treatment option.
7 citations
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January 2012 in “International Journal of Trichology” This article highlights differences in childhood alopecia areata compared to adult cases but reports no new clinical findings.
July 2004 in “Dermatologic Surgery” This study identified acute localized telogen effluvium as a potential cause of temporal hair loss following rhytidectomy.
31 citations
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March 2017 in “Journal of The American Academy of Dermatology” This study observed various patterns of permanent alopecia in breast cancer patients treated with taxanes and adjuvant hormonal chemotherapy, hypothesizing disruptions in hair follicle cycles due to chemoinflammatory and hormonal factors.
7 citations
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December 2016 in “British Journal of Dermatology” This report presents evidence that alopecia areata incognita may be a possible mechanism of hair loss in patients with Cronkhite–Canada syndrome.