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The document reviews key historical figures and discoveries in dermatology.

Mutations in the P2RY5 gene cause hereditary woolly hair.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Treatments for melanin disorders exist, but more effective options needed.

The conclusion is that individual differences in COVID-19 severity are influenced by factors like age, sex, race, and genetics, which are important for personalized medicine.

Artesunate is generally safe for severe malaria, but patients should be monitored for delayed anemia after treatment.

Toxic epidermal necrolysis is a severe skin reaction often linked to drugs, requiring careful medication use and supportive care.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Some herbs show promise as antiandrogenic agents.

Polyamines are important for hair growth, but more research is needed to understand their functions and treatment potential.

The document concludes that accurate diagnosis and treatment of scalp itch require differentiating between various conditions using a proposed five-step evaluation process.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Many skin patients also have mental health issues, and doctors should treat both together.

Alopecia areata, a type of hair loss, is likely an autoimmune disease with a genetic link, but its exact cause is still unknown.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

Juniperus plants contain compounds with potential for developing various medical treatments.

Skin problems in older people can indicate hormonal diseases, nutritional deficiencies, or conditions like diabetes, menopause, and HIV.

An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Hair follicles are essential for skin health, aiding in hair growth, wound healing, and immune function.

Oral contraceptives may cause hair loss in women.

The article concludes that dermatologists should prescribe lifestyle drugs carefully and consider mental health treatments for patients with disorders like BDD.

A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.

A kidney transplant patient on cyclosporin experienced unexpected severe hair loss, which improved with treatment adjustments.

Deslorelin may help intact male dogs regrow hair from alopecia X, with a 75% success rate and no side effects.