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Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

Tofacitinib and ruxolitinib are effective and safe for treating various autoimmune skin and joint disorders.

Spironolactone is a low-cost, effective, and generally safe treatment for various skin conditions related to hormones.

Caffeine improves hair growth, thickness, and reduces shedding.

WNT7A gene expression is higher in early stages of androgenetic alopecia, showing the role of WNT pathway, apoptosis, and inflammation in the disorder.

PRGF treatment is safer and more effective for hair loss than topical minoxidil.

Finasteride-loaded ethosomes improve hair loss treatment by targeting pilosebaceous unit.

Some breast cancer patients on hormone therapy experience hair loss, and treatments like certain topical inhibitors and supplements may help without harming their cancer prognosis.

PRGF treatment safely and effectively helps hair loss.

Transdermal testosterone can improve sexual desire in postmenopausal women but lacks long-term safety data and is not FDA-approved for this use.

Check and treat low iron and vitamin D levels in people with hair loss.

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.

Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.

Triptorelin helps evaluate hormone production in Sertoli-Leydig cell tumors.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

The skin has about 230,000 touch-sensitive nerve fibers, with high concentrations in the hands and face.

PRP injections safely increase hair density and thickness in androgenetic alopecia.

Serenoa repens may cause early puberty and should be used cautiously in children.

The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

JAK inhibitors for alopecia areata are linked to minor side effects like headache and acne, but not to an increased risk of serious adverse events.

Paeoniflorin protects brain cells by involving a specific protein and neurosteroids.

A woman with Cushing's syndrome improved after surgery to remove a tumor causing the condition.

The number of advanced breast cancer cases in women under 40 has increased, but the overall numbers are still low.

Hormones significantly affect women's sexual function, and more research is needed to improve treatments for sexual dysfunction with minimal side effects.

Cytokines are important for immune responses and treating diseases, but they can cause side effects like fever and skin issues.

Platelet-rich plasma (PRP) speeds up skin wound healing and has potential in medical and cosmetic uses.