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Testosterone therapy can modestly improve sexual function in menopausal women but should be used cautiously and is not recommended for routine measurement in sexual dysfunction or hirsutism.

Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Many women with hair loss also have thyroid issues, high blood pressure, and low Vitamin D.

Acne and increased body hair in teenage girls are normal but severe cases may need hormone evaluation and treatment can prevent diabetes linked to PCO.

Hidradenitis suppurativa may be related to hormones and patients often have metabolic disorders; more research is needed to understand this connection.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Spironolactone can reduce hair growth and testosterone in hirsutism, but is less effective than combined treatments.

Continuing education programs significantly increased rural nurse practitioners' knowledge about PCOS.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Obesity is common in PCOS patients and early treatment is important for their heart and metabolic health.

Understanding and manipulating epigenetic changes can potentially lead to human organ regeneration therapies, but more research is needed to improve these methods and minimize risks.

FPHL is common in women, influenced by genetics and hormones, and can be treated with medications, laser therapy, or hair transplantation.

Primary care doctors should address female sexual dysfunctions to improve women's sexual health and life quality.

A protein called sFRP4 can slow down hair regrowth.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Male pattern baldness does not cause an increased risk of prostate cancer.

Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.

CD99 is highly present in certain skin cells and could help treat skin conditions.

Many women with hard-to-treat acne also have PCOS.

The document reports three sisters with Woodhouse-Sakati syndrome showing typical symptoms and unusual gynecological anomalies.

Sex neurosteroids cause different effects on hippocampal synaptic plasticity in males and females.

Microneedles with extracellular vesicles show promise for treating various conditions with targeted delivery.