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Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Insulin resistance contributes to hormone imbalances in many women with polycystic ovary syndrome.

People with polycystic ovary syndrome have a higher chance of having chronic thyroiditis.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Spironolactone is an effective and well-tolerated first-line treatment for hidradenitis suppurativa in women.

A woman's mature cystic teratoma caused her virilization by producing testosterone.

Genetic mutations can affect female sexual development, requiring personalized medical care.

PCOS is a hormonal disorder causing infertility and menstrual problems, often linked to obesity and can lead to acne, treated with hormonal and insulin-sensitizing medications.

PEGylated liposomal doxorubicin improves cancer treatment effectiveness and reduces side effects like heart damage and hair loss.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

The study found no significant difference in stress hormone levels between people with alopecia areata and healthy individuals, suggesting that the disease is not caused by an overactive stress response system.

Oral contraceptives provide various health benefits beyond birth control, including managing menstrual issues, skin conditions, pain, and reducing the risk of certain cancers.

Some steroid-induced health issues in rodents improved after stopping treatment, but hair loss and eye problems did not.

Hirsutism requires identifying the cause to choose the right treatment, which may include medications like oral contraceptives or dexamethasone.

Most women with too much androgens have PCOS, which can be managed with birth control pills, medication for hair growth, and fertility treatments, and losing weight helps too.

Chemotherapy is crucial for treating gynecological cancers but requires careful management due to severe side effects.

Hirsutism, often caused by PCOS, is treated with medication and weight loss is important for obese women with PCOS.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

KRT80 may worsen cancer by increasing growth and spread, but its full effects on treatment and outcomes need more research.

Acne treatment with isotretinoin increases the presence of p53, a protein, in skin and oil glands, which may help reduce acne severity.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

Old drugs are often used for new, different medical purposes in endocrine pharmacology.

Polycystic ovary syndrome, a disorder causing menstrual issues and infertility, can be treated with lifestyle changes, medication, herbal remedies, surgery, and assisted reproductive techniques like artificial insemination and IVF.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

More research is needed to understand how testosterone is maintained in adult males.

Insulin resistance increases the risk of developing type 2 diabetes and other health issues.

The document concludes that managing hirsutism in PCOS involves long-term treatment guided by severity, using oral contraceptives and possibly antiandrogens, with attention to individual patient needs.