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The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

The review found no clear link between vitamin D receptor gene variations and polycystic ovary syndrome.

Eating disorders can cause skin problems that need treating the underlying condition for better health.

Women with female pattern hair loss have higher levels of certain androgens, suggesting increased androgen exposure to hair follicles.

LPA3 is crucial for embryo implantation and links LPA to prostaglandin signaling.

Men with common hair loss may have a higher risk of heart disease and diabetes, and should be checked for these conditions.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

The nafarelin test can reliably distinguish between gonadotropin deficiency and delayed puberty in teenage boys.

Low-dose finasteride reduces excessive hair growth in teenage girls safely and affordably.

Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.

Treatment can improve survival and symptoms in dogs with Cushing's disease, but outcomes are unpredictable.

Many elderly women experience unwanted facial hair and various hair loss conditions, with treatments available for each condition.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.

Sexual orientation does not affect the prevalence of PCOS or fertility rates in women undergoing artificial donor insemination.

Healthcare providers need better education and policies to serve transgender individuals effectively.

Plant-based remedies may treat hair loss by reducing inflammation and improving insulin resistance.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

Women with polycystic ovary syndrome have a higher risk of certain fractures.

Blood tests are needed to confirm high male hormone levels in women with PCOS, as physical signs alone are not reliable.

The conclusion is that a thorough approach is needed to diagnose and manage hyperandrogenism in teenage girls, recognizing its major psychological and health effects.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

The document concludes that treating female hair loss should target reducing excess androgen and blocking its effects on hair follicles, with the best treatments being hormonal therapy, adrenal suppression, and topical minoxidil.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

Chemotherapy causes complex changes in hair follicle cells that can lead to hair loss.