May 2022 in “The Journal of Sexual Medicine” In this retrospective study at Toyama University Hospital, amoxapine was reported to significantly improve semen volume, sperm concentration, and total sperm count in 17 men with ejaculatory disorders, with no observed side effects over an average of 13 months of therapy.
228 citations
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February 2003 in “Urology” This article discusses the side effects of androgen deprivation therapy for nonmetastatic prostate cancer, highlighting the need for clinical trials to systematically study these effects.
2152 citations
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November 2013 in “Urologia Internationalis” This study reviews the significant prevalence of organic etiologies, especially vascular causes, in erectile dysfunction among men under 40 and emphasizes thorough evaluation and consideration of treatment options like exercise and PDE-5 inhibitors.
5 citations
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June 2020 in “Journal of Endocrinological Investigation” The study observed that women with congenital adrenal hyperplasia experience more impaired sexual functions and are more often homosexually or bisexually oriented than those with polycystic ovary syndrome.
May 2025 in “International Journal of Nursing Education and Research” In this qualitative study, researchers explored the impact of hyperandrogenism on young female adults, identifying themes including appearance-related challenges, emotional distress, social support issues, and insufficient knowledge, which all affect well-being.
11 citations
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July 2019 in “The Journal of Sexual Medicine” This study suggests that spironolactone may cause hormonally associated vestibulodynia and female sexual arousal disorder, with symptoms improving after discontinuation and use of a topical estrogen/testosterone gel.
November 2022 in “Journal of the Endocrine Society” This case study highlights the complexity of managing PCOS and its symptoms in transmen, suggesting hormonal fluctuations may lead to symptomatic relief with low dose estradiol.
January 2025 in “Journal of Men s Health” This article reports that the rise in erectile dysfunction among young men may be linked to mental health issues and societal pressures, with online communities often encouraging risky substance use like anabolic steroids and finasteride, which can exacerbate psychological and physical health problems.
11 citations
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August 2019 in “The Journal of Sexual Medicine” This study found that women with nonclassic congenital adrenal hyperplasia (NC-CAH) reported lower sexual function and higher sexual distress compared to those with classic CAH (C-CAH), particularly among those showing signs of androgen excess.
3 citations
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September 2000 in “Geriatric nursing” This review summarizes key characteristics of men's health issues such as erectile dysfunction and prostate cancer, along with specific nursing considerations, and reports no new research results.
April 2016 in “The Journal of Sexual Medicine” PFS affects some women, steroids easily bought online, hypogonadism info unreliable, low testosterone linked to CVD.
55 citations
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January 2007 in “Climacteric” This paper reviews guidelines discussed at a meeting about research and practice themes, but reports no new research findings.
7 citations
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June 2006 in “Pediatrics in Review” This review covers gynecologic examination challenges and normal anatomical variations in prepubertal girls, emphasizing the importance of distinguishing common benign conditions from rare abuse cases; it presents no new experimental findings.
January 2023 in “Mastology” This literature review reports prevalent sexual dysfunctions, notably vaginal dryness, in women undergoing endocrine therapy for hormone-dependent breast cancer, highlighting the need for more multidisciplinary research and care to improve patient well-being.
January 2026 in “JCEM Case Reports” This case study describes two postmenopausal women with severe androgen excess symptoms, diagnosed with ovarian hyperthecosis and stromal hyperplasia, emphasizing the challenges in differentiating these benign conditions from androgen-secreting tumors and the importance of surgical and histopathological evaluation for correct diagnosis and management.
1 citations
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July 2013 in “JAMA Dermatology” This abstract is a website placeholder and reports no research findings or results; it contains navigation and policy information for JAMA Dermatology.
October 2011 in “InTech eBooks” This article reviews idiopathic hypogonadotropic hypogonadism (IHH), discussing its genetic and pathophysiological features, and it does not present new clinical results.
January 2026 in “Journal of Pharmacy & Bioresources” This study found that 44.3% of patients with benign prostatic hyperplasia experienced high anxiety levels, which were significantly associated with residual symptoms and demographic factors.
5 citations
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April 2016 in “PubMed” This study found that men aged 18-40 with moderate to severe psychosocial impairment from male androgenetic alopecia had a higher risk of sexual dysfunction.
This review outlines common dermatological disorders in transgender patients related to hormone therapy and surgeries but presents no new clinical findings; the authors emphasize the need for inclusive healthcare training.
1 citations
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August 2025 in “Cureus” This review synthesizes evidence on the prevalence, impacts, causes, and treatment of erectile dysfunction in men under 40 but reports no new clinical results; the authors emphasize the need for comprehensive evaluation and individualized care.
11 citations
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January 2016 in “The Journal of Sexual Medicine” This study found that young women with nonclassic congenital adrenal hyperplasia had impaired sexual function and mild depressive symptoms compared to healthy women.
22 citations
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January 1995 in “The American Journal of Medicine” This article reviews the negative effects of androgenic disorders and highlights that newer oral contraceptives with less androgenic progestins may reduce these effects and improve compliance, but it reports no new results.
43 citations
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January 2016 in “International Journal of Andrology” This study found that men experiencing long-term symptoms after finasteride use for androgenetic alopecia frequently reported loss of penis sensitivity and anhedonia, among other effects, indicating potential post-finasteride syndrome.
26 citations
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December 2019 in “Neurobiology of Stress” This review discusses adverse effects of 5 alpha-reductase inhibitors, particularly persistent side effects such as post-finasteride syndrome, and highlights the need for further investigation.
April 2019 in “Journal of the Endocrine Society” This case study highlights the importance of considering broad causes when evaluating hot flashes in middle-aged men, as it detailed a pituitary macroadenoma causing secondary hypogonadism in a man presenting with such symptoms.
April 2026 in “International Journal of Impotence Research” This review outlines the major health consequences of anabolic-androgenic steroid abuse, with a focus on sexual and reproductive issues, and suggests management prioritizes cessation and relapse prevention due to lack of robust randomized trials.
28 citations
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November 2017 in “Molecular and cellular endocrinology” This review examines the roles of testosterone, dihydrotestosterone, and estradiol in activating male sexual behavior in laboratory animals and humans, reporting no new clinical results.
21 citations
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November 2018 in “Journal of Psychosomatic Obstetrics & Gynecology” This study found that women with PCOS exhibited higher levels of alexithymia and body uneasiness compared to healthy controls, affecting their psychological and social well-being.
December 2025 in “Pakistan Journal of Health Sciences” This systematic review found that estrogen deficiency in postmenopausal women leads to structural and symptomatic changes in genital and cutaneous tissues, with local estrogen therapy providing short-term benefits, while evidence for device-based treatments remains limited and requires larger trials.