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The conclusion is that formalizing how past decisions influence current health technology assessments could improve the credibility and defense of coverage decisions.

Minoxidil may cause heart issues in animals and humans.

Existing drug dexamethasone may lower death risk in severe COVID-19 cases; more research needed for other drugs.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.

Madarosis is the loss of eyelashes and eyebrows due to various health issues and requires thorough examination to diagnose and treat the underlying cause.

Cromakalim relaxes various blood vessels, while minoxidil sulphate is more selective; they likely act on different potassium channels.

Thymic transplantation normalized some T-cells but not others, maintaining immune function.

New hair transplant methods offer more natural results and better graft survival, with ongoing research to increase donor hair options.

Mice without the Sp6 gene have problems developing several body parts, including hair, teeth, limbs, and lungs.

Skin organoids are a promising new model for studying human skin development and testing treatments.

Patient-derived melanocytes can potentially treat vitiligo by restoring skin pigmentation.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.

MALDI Imaging Mass Spectrometry is a useful method for studying skin conditions, but sample preparation is crucial for accurate results.

Small changes in hormones can significantly impact health, showing the importance of sensitive testing for chemicals that disrupt hormones.

IGF-1 may affect hair growth and loss, but more research is needed to confirm effective and safe treatments.

Hormone therapies like birth control pills and spironolactone are safe and effective for treating women's adult acne.

Rats had lasting erectile problems after stopping a certain medication.

Minoxidil use during pregnancy may cause fetal harm.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Further research is needed to improve hair regeneration using stem cells and nanomaterials.

Certain skin conditions can indicate insulin resistance and should prompt lifestyle changes and medical treatment to manage underlying health issues.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.

Researchers created early-stage hair-like structures from skin cells, showing how these cells can self-organize, but more is needed for complete hair growth.

New drugs for heart disease may be developed from molecules secreted by stem cells.