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Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Vitamin D3 analogs can promote hair growth in mice genetically prone to hair loss.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

Scalp cooling is largely ineffective in preventing hair loss from breast cancer chemotherapy.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

Male rats grow hair faster than females, and certain hormones can slow or slightly increase hair growth, but not significantly beyond natural rates.

Testosterone applied to rabbit skin increases skin cell growth and changes skin structure.

Certain SHBG gene variants, like rs727428, are linked to higher testosterone levels in women with PCOS.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

New compounds can block testosterone effects in rats and might help treat conditions like prostate cancer and acne.

No definitive link between finasteride and male breast cancer, but further research is needed.

Certain sex hormones and antiandrogens can either slow down or speed up the growth of human hair follicle cells depending on their concentration.

Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

Progestogens are essential in menopausal hormone therapy to prevent uterine cancer and must be chosen carefully based on individual needs.

The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.

Thyroid hormone treatments help thyroidectomized rats grow normally.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Cyclosporine A therapy changes sex hormone levels differently in pre-menopausal and post-menopausal women with primary biliary cirrhosis.

Certain genetic variants are linked to frontal fibrosing alopecia in Spanish patients.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

Anti-IL-1 treatments might help with certain types of hair loss in people with high inflammation.

Alopecia patients have a less active liver monoxygenase system, which can be treated with photochemotherapy and system inducers.

Psychological factors play a significant role in developing alopecia areata.