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In this report, an 18-year-old female with trichotillomania was successfully treated using the glutamate modulator n-acetylcysteine.

Ritlecitinib shows promise for treating alopecia areata, especially with early and extended treatment.

This Cochrane review reports that 5-alpha reductase inhibitors may slightly reduce urological symptoms and acute urinary retention risk compared to placebo, with a possible small reduction in surgical intervention need compared to alpha blockers.

Certain gene variations in EGF and EGFR may increase the risk of alopecia areata in Koreans.

In this study, the use of 5 alpha reductase inhibitors was associated with an increased risk of dementia during the first two years of treatment, but the risk was not significant with longer exposure.

The researchers reported two brothers with a new variant of X-linked trichothiodystrophy associated with an RNF113A gene mutation, highlighting features such as intellectual disability and growth failure, but without previously reported endocrinological or genital abnormalities, underlining the importance of genetic counseling for such variants.

This case study documents the co-existence of trichorhinophalangeal syndrome and loose anagen syndrome in a patient, highlighting a previously unreported association between the two conditions.

This report from a consensus meeting concluded that while 5-alpha reductase inhibitors are beneficial for BPH treatment and prostate cancer risk reduction, their role in clinical practice should be more widely integrated into prostate management guidelines.

In this study, researchers developed an open-source browser-based tool to enhance the reproducibility and accuracy of SALT score calculations from scalp photos, aimed particularly at assessing partial regrowth in alopecia areata patients on JAK inhibitor therapy.

In this study, 95% of respondents reported severe hair breakage or loss after using the Rio Hair Naturalizer System, with many experiencing significant and lasting hair loss.

This article discusses the emergence of "Kainar syndrome" among residents near a nuclear test site in Kazakhstan and names brucellosis combined with vitamin deficiency as the suspected cause, without attributing it to nuclear tests.

This study found that naltrexone did not significantly reduce hair pulling in adults with trichotillomania compared to placebo, although it improved cognitive flexibility.

This study found that activating the Nrf2 pathway in human mast cells effectively suppresses degranulation and inflammation induced by substance P.

This announcement outlines job opportunities at the Anderson Center for Hair and provides no clinical research findings.

In this study, ritlecitinib 50-mg showed clinically meaningful efficacy, with improvements in the Severity of Alopecia Tool score observed in patients with alopecia areata over a 3-year period, demonstrating long-term benefit in both clinician- and patient-reported outcomes.

In this study, researchers developed a near-infrared-responsive nanoplatform that synergistically enhances chronic wound healing by accelerating mitochondrial restoration and immune modulation, leading to enhanced wound repair and high-quality healing in diabetic rat models.

This article reports a case of a 14-month-old child with a constriction ring syndrome caused by tightly wrapped hair, highlighting the importance of early recognition and treatment to prevent serious complications.

This study found that expressions of TLR-3, TLR-7, TLR-8, and TLR-9 were significantly higher in alopecia areata patients compared to healthy controls, indicating a potential role in disease autoimmunity.

This case report illustrates that pellagra can develop in patients with anorexia nervosa without typical signs of severe malnutrition, responding rapidly to nicotinamide and tryptophan therapy.

This case study reported that a 15-year-old female developed acquired localized trichorrhexis nodosa, a hair shaft disorder, due to vigorous rubbing of an herbal powder on her scalp as part of local cultural practices.

This study observed an increase in hair thickness and reduced hair loss in patients with androgenetic alopecia after treatment with autologous cellular suspension using the Rigenera® system, though further research is needed.

This study found that African American men with prostate cancer have higher rates of somatic and germline androgen receptor mutations than Caucasian American men, which may contribute to ethnic differences in disease progression and outcomes.

This study utilized a sequence-structure alignment approach to improve the characterization of Class A Rhodopsin GPCR superfamily, including orphan and unclassified receptors, through evolutionary analysis.

This study reveals that long non-coding RNAs influence cashmere fiber traits in goats by interacting with target genes involved in pathways affecting fiber diameter and color.

This study evaluates the efficacy and safety of a higher dose (100-mg) of ritlecitinib for treating severe alopecia areata, comparing it to external and synthetic placebo control groups.

This review focuses on neuroactive steroids' influence on GABA-ergic signaling and discusses challenges in developing them for various therapeutic uses, citing recent excitement from FDA approval of allopregnanolone for postpartum depression but reporting no new results.

This study found that the enzyme A20 helps regulate EDAR-induced NF-κB signaling in mice, preventing ectodermal abnormalities like disheveled hair and assuring proper skin and appendage development.

This animal study observed that treatment with the S1PR modulator NXC736 significantly reduced lesion area and CD8+ T cell infiltration in mice with alopecia areata, suggesting its potential as a promising therapy for the condition.

This study found that alopecia areata was associated with increased serum levels of retinol-binding protein-4 compared to controls, but no correlation with disease severity was observed.

Finasteride may help improve certain brain function issues linked to dopamine.