April 2018 in “Journal of Investigative Dermatology” This study found that sensitive scalp is characterized by increased pH levels, redness, altered sebum composition, and a disrupted microbiome, suggesting these features could inform treatment approaches.
124 citations
,
April 1992 in “Journal of Endocrinology/Journal of endocrinology” This study observed that cells from androgen-sensitive areas like the beard and scrotum showed higher androgen receptor levels compared to those from non-balding scalp areas, supporting the role of dermal papilla in follicle growth responses to androgens.
15 citations
,
February 2003 in “British Journal of Dermatology” This study demonstrated that using morphometric and 3D reconstruction software to evaluate scalp biopsies in non-cicatricial alopecias may be feasible and sensitive for detecting subtle follicular changes.
12 citations
,
May 2021 in “Clinical Interventions in Aging” This study found that men with androgenetic alopecia have different scalp biophysical characteristics in androgen-sensitive areas compared to non-sensitive areas and healthy controls.
This review discusses various non-invasive methods for diagnosing alopecia areata, highlighting that trichoscopy signs like short vellus hairs and yellow dots are sensitive indicators of the condition, while advanced imaging techniques provide valuable information on hair follicle status and scalp inflammation.
34 citations
,
April 2016 in “International Journal of Dermatology” In this study, certain trichoscopic features were found to be sensitive and specific for diagnosing primary cicatricial alopecias and its subtypes using dermatoscopy.
28 citations
,
November 2017 in “Skin appendage disorders” This paper proposes a systematic approach to evaluating scalp itch using the SCALLP acronym and highlights the importance of classifying cases based on the presence of dermatological lesions and hair loss, but it reports no new clinical findings.
4 citations
,
February 2021 in “International Journal of Women's Dermatology” This study determined that trichoscopy is a sensitive and specific tool that effectively aids in diagnosing alopecia in women, especially when clinical diagnosis is uncertain.
10 citations
,
January 2013 in “International Journal of Trichology” This study found that trichoscopy using anisotrichosis criteria was 75% sensitive and 61.54% specific in diagnosing early female pattern hair loss in women without visible hair thinning.
May 2021 in “Pakistan Journal of Medical and Health Sciences” This review discusses how trichoscopy is becoming a preferred non-invasive diagnostic tool over trichograms for evaluating hair disorders, although it reports no clinical results.
October 2022 in “Gadua Journal of Pure and Allied Science” In this study, Trichophyton tonsurans and Microsporum canis were identified as the primary causes of tinea capitis, with terbinafine treatment showing the highest cure rate. Non-commercial kits surpassed real-time PCR commercial kits in specificity and sensitivity for diagnosis.
July 2019 in “Journal of the European Academy of Dermatology and Venereology” This study reported no measurable effect on libido or other sexual life parameters in finasteride users compared to non-users among male participants examined with the Arizona Sexual Experience scale.
93 citations
,
February 2015 in “Journal of Investigative Dermatology” This study suggests that oxidative stress may contribute to androgenetic alopecia by inducing premature senescence and secretion of hair growth inhibitors in dermal papilla cells from balding scalp.
17 citations
,
December 2004 in “The Journal of Men's Health & Gender” This article discusses the role of androgens in hair follicle changes, explaining how dihydrotestosterone contributes to hair thinning on the scalp, while promoting thicker facial hair in men, and reports no new clinical results.
141 citations
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November 2007 in “Journal of Investigative Dermatology” This study found that balding dermal papilla cells show premature senescence and altered expression of stress and DNA damage markers, suggesting sensitivity to environmental stress in androgenetic alopecia.
80 citations
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March 2008 in “Contact Dermatitis” This study found that scalp sensitivity frequently occurs in the French population and is associated with various symptoms and triggers, differing from facial skin sensitivity.
September 2023 in “Clinical, cosmetic and investigational dermatology” In this study, the researchers found that a 28-day topical treatment with a postbiotic ferment complex notably altered the scalp microbiome in women with sensitive scalps, increasing certain bacterial species and decreasing others, while also reportedly alleviating symptoms of sensitive skin syndrome in all participants.
15 citations
,
January 2017 in “Lasers in Surgery and Medicine” In this study, four male patients with extensively photodamaged scalps showed a 60-90% improvement in dyspigmentation, lentigines, and keratosis after a single treatment with the fractionated 1,927 nm thulium fiber laser, with no adverse events observed.
June 2023 in “International journal of pharmaceutical quality assurance” This study found that videodermoscopy is a promising non-invasive tool for distinguishing between types of non-scarring alopecia on the scalp, highlighting its potential in dermatological practice.
August 2017 in “Journal of evolution of medical and dental sciences” In this study, researchers evaluated trichoscopy in diagnosing non-scarring alopecia and found diagnostic value in observing diverse hair diameters in androgenetic alopecia, black dots and broken hairs in alopecia areata, and empty follicles in telogen effluvium, supporting trichoscopy's utility in differentiating alopecia types.
10 citations
,
November 1997 in “British Journal of Dermatology” This study found that the non-steroidal antiandrogen RU58841 increased hair growth rates and promoted hair cycle initiation in balding human scalp grafts on testosterone-conditioned nude mice, indicating a positive effect on hair growth.
22 citations
,
May 2002 in “Skin Research and Technology” This study found that in male androgenetic alopecia, the contrast enhanced phototrichogram technique was superior in detecting changes in hair density and thickness compared to other methods.
8 citations
,
March 2017 in “Experimental Dermatology” In this exploratory study, researchers found slightly increased levels of inflammatory markers in scalp skin affected by androgenetic alopecia, suggesting differential gene expression involved in hair cycle and keratin production.
227 citations
,
January 1998 in “Journal of Endocrinology” This study found that dermal papilla cells from balding scalp hair follicles have significantly higher levels of androgen receptors than those from non-balding follicles, supporting their in vivo androgen response.
19 citations
,
March 1996 in “British Journal of Dermatology” This study found that dermal papilla cells from balding follicles exhibit distinct growth characteristics compared to non-balding cells, suggesting their potential as a model for understanding androgenetic alopecia.
46 citations
,
June 2018 in “American Journal of Clinical Dermatology” This review summarizes the clinical, trichoscopic, and histopathological features of alopecia types associated with cutaneous and systemic lupus erythematosus and explores their links to disease activity, but it reports no new clinical results.
February 2025 in “Skin Research and Technology” This study highlights the potential of novel non-invasive testing techniques to enhance the diagnosis, treatment, and care of scalp hair diseases, urging future research to improve their accuracy and efficiency.
17 citations
,
May 2003 in “Journal of The American Academy of Dermatology” This study found that miniaturized hair follicles from pattern alopecia can regenerate rapidly when transplanted onto mice and may grow as well as or better than terminal hairs.
14 citations
,
September 2016 in “Journal of Cutaneous Pathology” This review discusses the classification and diagnosis of primary scalp alopecia, focusing on scarring and non-scarring types, and reports no new clinical results; it emphasizes simplified diagnostic pathways and tissue processing techniques.
10 citations
,
December 2010 in “British Journal of Dermatology” This study reports two distinct patterns of hair changes in postmenopausal women, linking diffuse generalized scalp hair loss to older age and frontal hair loss to higher facial hair scores and younger age.