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Stem cell niches support, regulate, and coordinate stem cell functions.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Stem cell self-renewal is complex and needs more research for full understanding.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.

Use minoxidil for hair loss treatment; assess results after 6 months.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Finasteride effectively treats baldness but may cause sexual side effects.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Male pattern hair loss is genetic and influenced by hormones, with treatments like minoxidil and surgery available.

One minoxidil-sensitive potassium channel exists in human hair follicles.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.