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The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

CDP is crucial for lung and hair follicle cell development.

Latanoprost can make eyelashes longer, thicker, and darker.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Tight junctions are key for skin protection and controlling what gets absorbed or passes through the skin.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Follicular Unit Extraction (FUE) is a less invasive hair transplant method with minimal scarring, suitable for about 60% of patients, especially those needing fewer grafts and quicker recovery.

Finasteride helps hair growth but may cause sexual side effects.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Humans lost body hair relatively recently in evolution.

Estrogen therapy can reduce skin aging but has cancer risks.

Stem cell self-renewal is complex and needs more research for full understanding.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.

Understanding hair follicle anatomy helps diagnose hair disorders.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

The drug IPI-926 is safe at 160 mg daily and may help treat certain tumors, especially basal cell carcinoma.

Forehead modification greatly increases the perception of femininity and is a safe procedure.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Surgery is the main treatment for liver hydatidosis, but has risks; albendazole is the most effective drug but can have side effects.

The document concludes that understanding hair structure is key to diagnosing hair abnormalities and recommends gentle hair care for management.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.