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    Glossary Nicotine

    highly addictive stimulant found in tobacco plants

    Nicotine is a highly addictive chemical compound found in tobacco plants. It acts as a stimulant in small doses, increasing heart rate and alertness, but can be toxic in larger amounts. Nicotine binds to nicotinic acetylcholine receptors in the brain, leading to the release of neurotransmitters like dopamine, which contributes to its addictive properties.

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    1. Melatonin protects cochlear hair cells from nicotine‐induced injury through inhibiting apoptosis, inflammation, oxidative stress and endoplasmic reticulum stress Basic & Clinical Pharmacology & Toxicology · 2021 · 5 citations
    2. HPTLC assay of nicotine and cotinine in biological samples Journal of Mind and Medical Sciences · 2018 · 2 citations
    3. Topically Applied Nicotinamide Inhibits Human Hair Follicle Growth Ex Vivo 2017 · 13 citations
    4. Determination of Vitamin B3 Vitamer (Nicotinamide) and Vitamin B6 Vitamers in Human Hair Using LC-MS/MS 2021 · 7 citations
    5. Oral Supplementation of Nicotinamide Mononucleotide (NMN) Improves Hair Quality and Subjective Perception of Hair Appearance in Middle-Aged Women Cosmetics · 2025
    6. Recombinant humanized collagen combined with nicotinamide increases the expression level of rat basement membrane proteins and promotes hair growth Frontiers in Bioengineering and Biotechnology · 2025
    7. Table 1_Recombinant humanized collagen combined with nicotinamide increases the expression level of rat basement membrane proteins and promotes hair growth.docx OPAL (Open@LaTrobe) (La Trobe University) · 2025
    8. Compatibility of Cetirizine Hydrochloride, Dutasteride, Hydrocortisone Acetate, Nicotinamide, Progesterone, and Pyridoxine Hydrochloride in TrichoSolTM, A Natural Vehicle for Hair Solutions. PubMed · 2024
    9. Compatibility of Caffeine Clobetasol Propionate Dutasteride Nicotinamide and Progesterone in TrichoFoam™, a Natural Vehicle for Hair Foams. PubMed · 2024
    10. 1115 Interrogating the gut-skin axis for acne and sebaceous gland health – a case study of nicotinic acid Journal of Investigative Dermatology · 2023
    11. 1317 Nicotinic acid suppresses sebaceous lipid synthesis of human sebocytes via activating hydroxycarboxylic acid receptor 2 (HCA2) Journal of Investigative Dermatology · 2018
    12. The effect of a dietary supplement containing nicotinamide (Cavalesse®), on the severity of the symptoms in horses suffering insect bite hypersensitivity. Utrecht University Repository (Utrecht University) · 2011
    13. Therapeutic effects of growth factor cocktail (CellcurinTM) containing FGF5s (fibroblast growth factor 5 short) and NMN (nicotinamide mononucleotide) in patients with androgenetic alopecia: A split study Global dermatology · 2020
    14. FC 2-2 : Therapeutic Effects of Growth Factor Cocktail (CellcurinTM) containing FGF5s (fibroblast growth factor 5 short) and NMN (nicotinamide mononucleotide) applied on the scalp in the patients with androgenetic alopecia: a split study 프로그램북(구 초록집) · 2020
    15. Alterations in scalp blood flow after the epicutaneous application of 3% minoxidil and 0.1% hexyl nicotinate in alopecia British Journal of Dermatology · 1987 · 25 citations
    16. β-Nicotinamide Mononucleotide Promotes Cell Proliferation and Hair Growth by Reducing Oxidative Stress 2024
    17. Neurosteroid allopregnanolone attenuates development of nicotine withdrawal behavior in mice Neuroscience Letters · 2013 · 8 citations
    18. Novel synthesis of nicotinamide derivatives of cytotoxic properties Bioorganic & Medicinal Chemistry · 2006 · 51 citations
    19. High-performance liquid chromatographic determination of α-tocopheryl nicotinate in cosmetic preparations 1992 · 5 citations
    20. 72707 Effects of Oral Nicotinamide Mononucleotide (NMN) Supplementation on Hair: Influence of Fatigue on Treatment Outcomes Journal of the American Academy of Dermatology · 2026
    21. Designed, Synthesis, In Vitro and Computational Analyses of Anticancer Nicotinamide Derivatives Indian Journal of Chemistry · 2024
    22. Influence of the cosmetic treatment of hair on drug testing International journal of legal medicine · 1997 · 157 citations
    23. Smoking and the skin International Journal of Dermatology · 2012 · 114 citations
    24. Tobacco and the skin Clinics in Dermatology · 2010 · 41 citations
    25. What causes acne inversa (or hidradenitis suppurativa)? – the debate continues Journal of Cutaneous Pathology · 2008 · 24 citations
    26. Implications of cigarette smoking on early‐onset androgenetic alopecia: A cross‐sectional Study Journal of Cosmetic Dermatology · 2020 · 7 citations
    27. What causes acne inversa (or hidradenitis suppurativa)? – The debate continues Journal of Cutaneous Pathology · 2008 · 5 citations
    28. Viewpoint 6 Experimental Dermatology · 2008 · 4 citations
    29. Smoker’s Mustache Revisited: Upper Lip Hair Yellow Discoloration Associated With Tobacco Cureus · 2021 · 3 citations
    30. Short Scar Rhytidectomy Techniques Atlas of the Oral and Maxillofacial Surgery Clinics · 2014 · 3 citations