research Melatonin Protects Cochlear Hair Cells from Nicotine-Induced Injury Through Inhibiting Apoptosis, Inflammation, Oxidative Stress, and Endoplasmic Reticulum Stress
Melatonin may protect ear cells from damage caused by nicotine.
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5 / 313 results research Neurosteroid Allopregnanolone Attenuates Development of Nicotine Withdrawal Behavior in Mice
The study investigated the effects of the neurosteroid allopregnanolone (ALLO) on nicotine withdrawal in mice. Mice subjected to chronic nicotine injections exhibited severe withdrawal symptoms, including somatic signs, anxiety, and reduced locomotion. However, pretreatment with ALLO or progesterone significantly mitigated these symptoms, an effect reversed by inhibitors of neurosteroid biosynthesis. ALLO administration during withdrawal did not affect withdrawal signs, suggesting its role in the development of nicotine dependence rather than withdrawal expression. The findings indicated that ALLO could be a potential pharmacological target for preventing nicotine relapse.
research The Clock Within: Molecular Clock in Epidermis Regulates Circadian Rhythms and Stem Cell Cycles
The circadian clock in skin cells controls their growth and rest cycles.
research The Current Landscape for Direct-to-Consumer Genetic Testing: Legal, Ethical, and Policy Issues
The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.
research Pharma in the Bedroom and the Kitchen: The Pharmaceuticalisation of Daily Life
The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.
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5 / 109 resultscommunity People who continue to lose hair on fin/dut, Are you on Nicotine?
Nicotine use, especially from vaping, may worsen hair shedding and reduce the effectiveness of finasteride and dutasteride. Quitting nicotine seems to improve hair health.
community Why visit Tressless if you actively despise medical treatment? (Fin/Dut/Min)
Finasteride, dutasteride, and minoxidil are discussed as effective hair loss treatments, with mixed opinions on their use and side effects. The conversation highlights a divide between supporting medical treatments and accepting baldness.
community Quit vaping/smoking = 80% less loss
Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.
community Are the japanese Finasteride 10 year studies even relevant to caucasian men - especially young ones?
The conversation is about the effectiveness of hair loss treatments, specifically finasteride and dutasteride, in different populations. Some users believe that the results of Japanese studies may not be relevant to Caucasian men, especially young ones, and that East Asians may respond better to these treatments. Others argue that clinical studies should be the basis for decision-making, while acknowledging that individual responses to medications can vary.
community Could low blood flow to the head cause an increased rate of thinning?
The user started using finasteride, minoxidil, and biotin for male pattern baldness (MPB) and is experiencing rapid thinning. They are questioning if low blood flow to the head could be contributing to their hair loss.