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The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

Higher levels of unbound testosterone are linked to increased insulin resistance, especially in women with polycystic ovary syndrome.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Activating TRPV3 stops human hair growth.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

Eating 500 fewer calories a day and making lifestyle changes can improve PCOS symptoms and reduce diabetes risk; more research is needed on its causes and treatments.

Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.