research MicroRNA-214 Controls Skin and Hair Follicle Development by Modulating the Activity of the Wnt Pathway
MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
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research Epidemiology of Skin Cancer in the Mature Patient
Older adults have a high rate of skin cancers like basal cell carcinoma and melanoma, mainly due to UV exposure and age.
research The Blastema and Epimorphic Regeneration in Mammals
Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
research Bioengineering a 3D Integumentary Organ System from iPS Cells Using an In Vivo Transplantation Model
Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
research Corneal Endothelial Cell Fate Is Maintained by LGR5 Through the Regulation of Hedgehog and Wnt Pathways
LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.
research The Silver Locus Product (Silv/gp100/Pmel17) as a New Tool for the Analysis of Melanosome Transfer in Human Melanocyte–Keratinocyte Co-Culture
The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.
research The Cycling Hair Follicle as an Ideal Systems Biology Research Model
The hair follicle is a great model for research to improve hair growth treatments.
research Choreographing Immunity in the Skin Epithelial Barrier
The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
research Keratinocytes Regulate the Function of Melanocytes
Keratinocytes control how melanocytes work.
research Stem Cell Markers (Cytokeratin 15, CD34, and Nestin) in Primary Scarring and Nonscarring Alopecia
Scarring alopecia affects different hair follicle stem cells than nonscarring alopecia, and the infundibular region could be a new treatment target.
research Brg1 Governs a Positive Feedback Circuit in the Hair Follicle for Tissue Regeneration and Repair
Brg1 is crucial for hair growth and skin repair by maintaining stem cells and promoting regeneration.
research Premature Graying of Hair: Causes, Associations, and Treatments
Premature graying of hair may suggest health issues and currently lacks effective treatments.
research Expression Patterns of MITF During Human Cutaneous Embryogenesis: Evidence for Bulge Epithelial Expression and Persistence of Dermal Melanoblasts
Melanocyte precursors in human fetal skin follow a specific migration pattern and some remain in the skin's deeper layers.
research Regulation of Melanocyte Stem Cells in the Pigmentation of Skin and Its Appendages: Biological Patterning and Therapeutic Potentials
Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.
research The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics
Tiny particles called extracellular vesicles could help with skin healing and hair growth, but more research is needed.
research Body Composition Changes and Inhibition of Fat Development In Vivo Implicate Androgen in Regulation of Stem Cell Lineage Allocation
Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.
research Cellular Senescence in Tissue Repair: Every Cloud Has a Silver Lining
Cell aging can be both good and bad for tissue repair.
research A Bald Statement: Current Approaches to Manipulate Miniaturization Focus Only on Promoting Hair Growth
The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.
research Meis1 Regulates Epidermal Stem Cells and Is Required for Skin Tumorigenesis
Meis1 is crucial for skin health and tumor development.
research Hair Growth Modulation by Adrenergic Drugs
Certain drugs can cause early hair growth in mice by affecting the nerves.
research Mesenchymal Stem Cells From Mouse Hair Follicles Reduce Hypertrophic Scarring in a Murine Wound Healing Model
Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
research Platelet-Derived Growth Factor Regulates the Proliferation and Differentiation of Human Melanocytes in a Differentiation-Stage-Specific Manner
PDGF-BB helps young melanocytes grow but stops mature ones from growing, and it makes melanocytes more specialized.
research Dermal EZH2 Orchestrates Dermal Differentiation and Epidermal Proliferation During Murine Skin Development
Dermal EZH2 controls skin cell development and hair growth in mice.
research Transcriptional Control of Epidermal Stem Cells
Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.
research Epithelial Loss of Mitochondrial Oxidative Phosphorylation Leads to Disturbed Enamel and Impaired Dentin Matrix Formation in Postnatal Developed Mouse Incisor
Mitochondrial problems in tooth cells lead to bad enamel and dentin development in mice.
research Effects of Gamma Rays on the Regeneration of Murine Hair Follicles in the Natural Hair Cycle
Gamma rays did not change hair follicle density but increased white and hypopigmented hairs in mice.
research Transplantation of Melanocyte Stem Cells in Vitiliginous Skin
Transplanting melanocyte stem cells from hair follicles can effectively treat vitiligo.
research Aging and Anti-Aging in Hair and Hair Loss
Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
research The Influence of Flightless I: Regeneration Versus Wound Healing
Blocking RANK signaling might help treat metastatic melanoma, but more research is needed.
research Regenerative Potential and Clinical Application of Mesenchymal Stem Cell-Derived Exosomes
MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.