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The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

The nude gene causes skin cell overgrowth and improper development, leading to hair and urinary issues.

Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Some breast cancer chemotherapy can cause permanent hair loss.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Hirsutism is excessive hair growth in women often caused by polycystic ovarian syndrome, and identifying the cause is important for managing associated health risks.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Inactive hair follicle stem cells help prevent skin cancer.

Children with scalp fungal infections need proper diagnosis and treatment, usually with antifungal medications, and newer drugs may offer quicker recovery.

Blocking BMP signaling causes hair loss and disrupts hair growth cycles.

Noggin overexpression delays eyelid opening by affecting cell death and skin cell development.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

Topical JAK inhibitors may help treat some skin conditions but need more research.

Evaluate postmenopausal women with high androgen levels using medical history, physical exams, lab tests, and imaging to manage health risks.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.

Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Sunlight worsens hair loss; protect scalp.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Apoptosis is crucial for healthy skin and treating skin diseases.