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Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Voriconazole can cause serious side effects, especially in long-term use.

AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

There is no standard treatment for the rare Cronkhite–Canada syndrome, which can be fatal and lead to cancer.

Alopecia areata patients, especially women with nail issues or atopic diseases, are at higher risk for other autoimmune diseases.

Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.

The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.

People with advanced chronic kidney disease often have skin problems, which can be treated with various medications and procedures to improve their quality of life.

Imiquimod improved skin pigmentation in most patients with xeroderma pigmentosum and may prevent further skin cancer, but some treatments can have side effects.

Skin, hair, and nail changes can help detect eating disorders early.

Thyroid disease can cause skin, hair, and nail problems, and treating the thyroid condition often improves these symptoms.

WNT10A helps esophageal cancer cells spread and keep renewing themselves.

FOXN1 gene variants cause low T cells and immune issues from birth.

The COVID-19 pandemic led to fewer dermatology visits and changed the types of skin conditions patients experienced.

Modified keratin binds better to hair, especially bleached hair.

Chronic kidney disease can cause skin problems that affect patient quality of life, and treating these conditions can improve outcomes.

A mix of tocopherol acetate and L-menthol helps grow hair better than using them separately or using minoxidil.

Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Adults with certain skin conditions may have higher levels of inflammation in their body.

Frontal fibrosing alopecia is a poorly understood condition with increasing cases and unclear treatment effectiveness.

Transglutaminase activity is important for skin and is found in both mammals and birds.

Collagen is crucial for health and treating certain diseases, and supplements can improve skin, nails, and hair conditions.

Platelet-rich plasma (PRP) is effective in treating various skin conditions and improving hair density, thickness, and patient satisfaction, with lower relapse rates for Alopecia Areata.

Vegan collagen builder improves hair growth, skin smoothness, and reduces wrinkles and pain.

Certain vitamins and their derivatives can help hair grow longer by activating specific growth signals.

Different rheumatological diseases can cause specific skin problems.

The document explains the genetic causes and characteristics of inherited hair disorders.

A 19-month-old boy with a rare hair disorder showed mild improvement with treatment, but his family chose gentle hair care due to limited success.