29 citations,
December 2019 in “Expert review of clinical pharmacology” JAK inhibitors are a promising new treatment for hair loss and nail problems in alopecia areata.
45 citations,
January 2018 in “International Journal of Dermatology” Nail problems are common in people with alopecia areata, often leading to cosmetic and functional issues, but more research is needed for treatment guidelines.
19 citations,
January 2018 Most people with alopecia areata have nail changes, which are common but don't greatly affect their quality of life.
May 2023 in “Clinical and Experimental Dermatology” Alopecia areata has a high chance of persisting and relapsing, with a significant risk of total hair loss, especially if it starts in childhood.
18 citations,
August 2018 in “The FASEB journal” Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.
44 citations,
July 2011 in “Dermato-endocrinology” Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.
111 citations,
November 2007 in “Clinics in Dermatology” Psoriasis skin changes are complex and might need several biopsies for a clear diagnosis.
26 citations,
June 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
53 citations,
September 2017 in “BMJ Open” Nearly all elderly nursing home residents had a skin disease, with dry skin being the most common.
June 2023 in “British Journal of Dermatology” Baricitinib was effective and safe for severe hair loss treatment over 6 months.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
17 citations,
January 2015 in “International Journal of Trichology” Frontal fibrosing alopecia may affect nails and could be a type of lichen planus, treatable with certain medications.
January 2015 in “Dermatology online journal” A man with total hair loss also developed a rare nail condition, likely due to autoimmune issues.
17 citations,
January 2010 in “Acta Dermato Venereologica” EGFR inhibitors can cause yellowish skin eruptions.
2 citations,
January 1996 in “Annals of saudi medicine/Annals of Saudi medicine” Alopecia areata is unpredictable, with limited treatment effectiveness, especially in severe cases.
1 citations,
October 2020 in “International Journal of Research in Dermatology” The study concluded that short vellus hair and yellow dots were the most common signs of alopecia areata, indicating disease activity and remission.
11 citations,
March 2016 in “Journal of the European Academy of Dermatology and Venereology” Almost all patients with chronic kidney disease not yet on dialysis have at least one skin problem.
December 2022 in “Journal of medical sciences and health” Examining nail biopsies is useful for diagnosing nail diseases.
31 citations,
September 2014 in “International Journal of Dermatology” Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.
September 2023 in “Journal of Cosmetic Dermatology” Minoxidil, a hair loss treatment, may help nails grow faster.
64 citations,
June 1992 in “International Journal of Dermatology” Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.
51 citations,
May 2008 in “Mycoses” Terbinafine HCl nail solutions with DDAIP HCl are more effective than current treatments for nail infections.
42 citations,
October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the KRT85 gene cause hair and nail problems.
22 citations,
January 2009 in “Advances in experimental medicine and biology” FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.
May 2022 in “Rossijskij žurnal kožnyh i veneričeskih boleznej” Alopecia areata is complex, often recurring, and needs personalized treatment, especially with other health issues.
19 citations,
May 2005 in “Archives of Environmental & Occupational Health” All immigrant workers in the study had skin problems, with fungal nail infections, athlete's foot, and acne or folliculitis being most common, affecting their quality of life, yet they didn't seek medical help.
13 citations,
August 1982 in “Archives of dermatology” A new side effect of aromatic retinoid treatment is soft nails.
September 2019 in “Journal of Investigative Dermatology” Smoking and certain health conditions like thyroid disease may make palmoplantar pustulosis harder to treat.
10 citations,
June 2021 in “BioMed Research International” Some recovered COVID-19 patients experience skin, hair, and nail issues, suggesting they need follow-up care.
10 citations,
January 2013 in “International Journal of Trichology” Systemic steroids effectively treated severe nail issues in a card illusionist with alopecia areata.