Alopecia Areata: Prognostic Factors

January 1996 in “ Annals of saudi medicine/Annals of Saudi medicine ”

Adnan S. Alabdulkareem, Abdulaziz A. Abahussein, Anezi N. Okoro

alopecia areata AA nail changes ophiasic type atopy hair regrowth

Studysummary This study found that severe forms of alopecia areata may be associated with poor treatment response, particularly in cases with extensive hair loss, juvenile onset, or nail changes.

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Research cited in this study

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research Juvenile Versus Maturity-Onset Alopecia Areata: A Comparative Retrospective Clinical Study

164 citations , November 1989 in “Clinical and Experimental Dermatology”

This retrospective study found that juvenile alopecia areata is more severe and has a worse prognosis than maturity-onset alopecia areata.

research Allergic and Irritant Contact Dermatitis Compared in the Treatment of Alopecia Totalis and Universalis: A Comparison of the Value of Topical Diphencyprone and Tretinoin Gel

36 citations , March 1989 in “British journal of dermatology/British journal of dermatology, Supplement”

In this study, the authors compared topical diphencyprone and tretinoin gel for treating alopecia totalis and universalis, but the abstract does not report any definitive clinical results.

research Treatment of Alopecia Areata With Squaric Acid Dibutylester

42 citations , August 1987 in “Archives of Dermatology”

In this study, 28.5% of patients with extensive alopecia areata had complete hair regrowth during treatment with squaric acid dibutylester, with outcomes linked to shorter alopecia duration and prompt dermatitis development.

research Topical Photochemotherapy for Alopecia Areata

63 citations , April 1985 in “Journal of the American Academy of Dermatology”

This study observed that topical PUVA treatment led to excellent or good hair regrowth in 45.4% of patients with alopecia areata, though many experienced relapse after treatment stopped.

research Alopecia Areata: Pathogenesis And Treatment

122 citations , November 1984 in “Journal of the American Academy of Dermatology”

This review discusses the potential autoimmune pathogenesis and various contributing factors of alopecia areata, noting that current treatments remain palliative while emerging therapies offer new hope for extensive cases.

research Immunohistochemical and Electron Microscopic Characterization of the Cellular Infiltrate in Alopecia Areata, Totalis, and Universalis

78 citations , July 1984 in “Journal of Investigative Dermatology”

research Decreased Lymphocyte Reactivity and Autoimmunity in Alopecia Areata

54 citations , August 1981 in “British Journal of Dermatology”

This study found that patients with alopecia areata had significantly lower T cell numbers and reduced lymphocyte responses compared to healthy controls, correlated with hair loss severity and presence of antithyroid antibodies.

research Alopecia Universalis, Onychodystrophy, and Total Vitiligo

31 citations , August 1963 in “Archives of Dermatology”

This report describes two patients with alopecia universalis, onychodystrophy, and vitiligo, and found no underlying systemic or etiological causes through extensive investigations.