13 citations,
June 2010 in “Journal of The American Academy of Dermatology” A man with Cronkhite-Canada syndrome had all 20 nails detach but improved with treatment.
35 citations,
November 1996 in “Journal of the American Academy of Dermatology” Itraconazole was effective in treating unusual M. canis infections in only one of two HIV-infected men.
10 citations,
October 2017 in “Pediatric neurology” Biotin and acetazolamide improved hair and nail growth, mental function, and reduced headaches in a child with autism.
29 citations,
December 2019 in “Expert review of clinical pharmacology” JAK inhibitors are a promising new treatment for hair loss and nail problems in alopecia areata.
3 citations,
January 2009 in “Elsevier eBooks” Soy can improve skin, hair, and nails.
19 citations,
January 2018 Most people with alopecia areata have nail changes, which are common but don't greatly affect their quality of life.
1 citations,
December 2019 Selenium is essential for health, but too much or too little can cause problems; blood selenium levels are a good measure of intake.
45 citations,
January 2018 in “International Journal of Dermatology” Nail problems are common in people with alopecia areata, often leading to cosmetic and functional issues, but more research is needed for treatment guidelines.
18 citations,
August 2018 in “The FASEB journal” Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.
May 2023 in “Clinical and Experimental Dermatology” Alopecia areata has a high chance of persisting and relapsing, with a significant risk of total hair loss, especially if it starts in childhood.
New cancer drugs can cause skin side effects like rashes, dry skin, hair changes, and nail problems.
44 citations,
July 2011 in “Dermato-endocrinology” Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.
111 citations,
November 2007 in “Clinics in Dermatology” Psoriasis skin changes are complex and might need several biopsies for a clear diagnosis.
26 citations,
June 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
53 citations,
September 2017 in “BMJ Open” Nearly all elderly nursing home residents had a skin disease, with dry skin being the most common.
January 2018 in “Springer eBooks” PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
June 2023 in “British Journal of Dermatology” Baricitinib was effective and safe for severe hair loss treatment over 6 months.
17 citations,
January 2015 in “International Journal of Trichology” Frontal fibrosing alopecia may affect nails and could be a type of lichen planus, treatable with certain medications.
January 2015 in “Dermatology online journal” A man with total hair loss also developed a rare nail condition, likely due to autoimmune issues.
17 citations,
January 2010 in “Acta Dermato Venereologica” EGFR inhibitors can cause yellowish skin eruptions.
2 citations,
January 1996 in “Annals of saudi medicine/Annals of Saudi medicine” Alopecia areata is unpredictable, with limited treatment effectiveness, especially in severe cases.
1 citations,
October 2020 in “International Journal of Research in Dermatology” The study concluded that short vellus hair and yellow dots were the most common signs of alopecia areata, indicating disease activity and remission.
11 citations,
March 2016 in “Journal of the European Academy of Dermatology and Venereology” Almost all patients with chronic kidney disease not yet on dialysis have at least one skin problem.
31 citations,
September 2014 in “International Journal of Dermatology” Anthralin is effective for psoriasis and alopecia with minimal systemic side effects but can irritate the skin.
September 2023 in “Journal of Cosmetic Dermatology” Minoxidil, a hair loss treatment, may help nails grow faster.
2 citations,
June 2018 in “Journal of the American Academy of Dermatology” Alopecia areata causes varying hair loss and nail changes, and treatments include topical, systemic, and injectable therapies.
51 citations,
May 2008 in “Mycoses” Terbinafine HCl nail solutions with DDAIP HCl are more effective than current treatments for nail infections.
42 citations,
October 2009 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the KRT85 gene cause hair and nail problems.
28 citations,
February 2010 in “British journal of dermatology/British journal of dermatology, Supplement” WNT10A mutations cause varied symptoms in patients with odonto-onycho-dermal dysplasia.
22 citations,
January 2009 in “Advances in experimental medicine and biology” FOXN1 mutations cause severe immunodeficiency, hair loss, nail issues, and thymus defects.