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The document explains hair and nail biology, common hair loss conditions and treatments, oral and genital skin diseases, and the risks and treatments associated with squamous cell carcinoma.

The document concludes that skin and nail changes can indicate various underlying health conditions.

Lupus can affect the scalp and nails, often causing hair loss and nail damage, and needs early aggressive treatment to prevent permanent damage.

An 8-year-old girl had nail and hair issues that improved without specific treatment, but fungal nail infection was hard to cure.

Intralesional triamcinolone acetonide is effective for treating patchy hair loss, and dermoscopy helps detect treatment response and side effects early.

Vitiligo patients often have nail problems, so checking their nails is important.

Looking at skin can help find and treat serious diseases early.

A man with Cronkhite-Canada syndrome had all 20 nails detach but improved with treatment.

Primary health care in Florianópolis mostly treated simple skin conditions, while secondary care handled more complex skin diseases.

Using neurohormones to control keratin can lead to new skin disease treatments.

Some recovered COVID-19 patients experience skin, hair, and nail issues, suggesting they need follow-up care.

Anti-cancer treatments can cause reversible hair loss, skin sensitivity, pigmentation changes, nail damage, and skin reactions, with a need for more research on managing these side effects.

Certain skin conditions in women are linked to higher risks of metabolic syndrome and type 2 diabetes due to hormone imbalances.

Chemotherapy with docetaxel can cause painful nail and skin side effects that may lead to stopping treatment.

People who get alopecia areata after age 50 usually have mild symptoms, high chances of hair regrowth, and often have other health conditions.

Customized medications made through compounding can be beneficial for various skin conditions but require careful regulation and collaboration between doctors and pharmacists.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.

DPCP helps treat severe hair loss, but 5% minoxidil doesn't add benefits.

Eating too many paradise nuts for cancer prevention caused a woman to lose all her hair due to selenium poisoning.

The visfatin GT genotype may increase the risk of Alopecia Areata.

Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.

The AIRE gene variant rs2075876 is linked to a higher risk of alopecia areata in males.

Patients with graft-versus-host disease often have nail changes related to the nail matrix, with severity not linked to skin condition.

Many hospitalized children with COVID-19 had skin, mouth, or nail changes, with skin rashes being common.

Alopecia areata patients, especially women with nail issues or atopic diseases, are at higher risk for other autoimmune diseases.

Chronic kidney disease can cause skin and nail problems.

Patients on hemodialysis commonly have skin color changes, nail problems, dry skin, and itching.

Stress, nutritional issues, and chronic diseases can cause hair loss, and nail changes may signal internal diseases; treatment focuses on the underlying cause.

The document concludes that while white skin, nail, and mucosa diseases increase skin cancer risk, they are generally harmless, especially compared to darker pigmentation conditions.