research A Regulatory Perspective on Pharmacokinetic/Pharmacodynamic Modelling
The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.
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research Who Benefits from Repealing Tampon Taxes? Empirical Evidence from New Jersey
Repealing tampon taxes helps low-income people the most by making menstrual products cheaper.
research Enhancing Hair Follicle Regeneration by Nonablative Fractional Laser: Assessment of Irradiation Parameters and Tissue Response
Using a fractional laser can stimulate hair growth, but the intensity and duration of inflammation are crucial. Too much can cause ulcers and scarring. Lower beam energy and fewer treatments are recommended to avoid damage.
research Application of Amber Filler for Production of Novel Polyamide Composite Fiber
Adding amber particles to polyamide fibers makes them suitable for medical textiles like compression socks.
research Photostability and Toxicity of Finasteride, Diclofenac, and Naproxen Under Simulated Sunlight Exposure: Evaluation of the Toxicity Trend and Packaging Photoprotection
Sunlight exposure increases drug toxicity; amber glass best for protection.
research Analyzing the Efficacy of Isotretinoin in Treating Dissecting Cellulitis: A Literature Review and Meta-Analysis
Isotretinoin is effective for treating dissecting cellulitis, but recurrence is common.
research Effects of Food-Derived Collagen Peptides on the Expression of Keratin and Keratin-Associated Protein Genes in Mouse Skin
Eating collagen peptides may help with skin and hair growth.
research Pathological Studies of Cross-Related Congenital Hypotrichosis in Cattle
Crossbreeding certain European cattle breeds may cause hair and physical issues in cattle.
research Transcriptome Sequencing and Identification of Cytochrome P450 Monooxygenases Involved in the Biosynthesis of Maslinic Acid and Corosolic Acid in Avicennia Marina
Researchers found two enzymes in Avicennia marina that help produce maslinic acid and corosolic acid, which have medicinal benefits.
research Expression of an Olfactomedin-Related Gene in Rat Hair Follicular Papilla Cells
FP-1 is a key protein in rat hair growth, active only during the growth phase.
research Phytochemical Studies on Traditional Herbal Medicines Based on Ethnopharmacological Information Obtained by Field Studies
Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.
research Intrinsic Versus Extrinsic Aging: A Histopathological, Morphometric, and Immunohistochemical Study of Estrogen Receptor β and Androgen Receptor
The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.
research Disruption of Anthrax Toxin Receptor 1 in Pigs Leads to a Rare Disease Phenotype and Protection from Senecavirus A Infection
Removing anthrax toxin receptor 1 in pigs prevents Senecavirus A infection and causes a rare disease similar to GAPO syndrome.
research Dermatologist and Patient Perceptions of Treatment Success in Alopecia Areata and Evaluation of Clinical Outcome Assessments in Japan
Both dermatologists and patients in Japan agree that treatment success for alopecia areata is having 20% or less scalp hair loss.
research Diversity of Vibrissal Follicle Anatomy in Cetaceans
Different whale and dolphin species have unique whisker follicle structures, suggesting they might use their whiskers in various ways.
research Function of KLF4 in Stem Cell Biology
KLF4 is important for maintaining stem cells and has potential in cancer treatment and wound healing.
research Secondary Amenorrhea: Causes, Diagnosis, and Treatment
Secondary amenorrhea has many causes and requires thorough evaluation to treat and restore menstrual cycles.
research Serendipity in Trichology
Accidental findings have led to new hair treatment discoveries, like using blood pressure and diabetes medications for hair loss and unwanted hair.
research Association Between 5-Alpha Reductase Inhibitor Use and the Risk of Depression: A Meta-Analysis
Using 5-alpha reductase inhibitors may increase the risk of mild depression.
research Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women
The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.
research Discovery of New Drug Therapies Based on the Study of Adverse Reactions
Side effects of drugs can lead to the discovery of new treatments.
research Mechanical Forces Across Compartments Coordinate Cell Shape and Fate Transitions to Generate Tissue Architecture
Mechanical forces are crucial for shaping cells and forming tissues during development.
research Global Expression Profile and Genome Methylation Signatures in Male Patients with Androgenetic Alopecia
Differences in gene expression and methylation patterns found in AGA patients suggest potential targets for future treatments.
research Dermatologic Adverse Events from Cancer Treatments
Cancer treatments can cause skin-related side effects that may affect patient quality of life and require changes in treatment.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
research Rapid Characterization of the Functional and Pharmacological Consequences of Cantú Syndrome KATP Channel Mutations in Intact Cells
Kir6.1 mutations in Cantú syndrome increase channel sensitivity and hyperpolarization, while SUR2B mutations do not.
research Revisiting the Significance of Keratin Expression in Complex Epithelia
Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.
research Azathioprine for the Treatment of Extensive Forms of Alopecia Areata: A Systematic Review
Azathioprine may help treat severe alopecia areata, but more research is needed.
research Hair Physiology: Hair Growth, Alopecia, Scalp Treatment, Etc.
The document concludes that new treatments for hair loss may involve a combination of cosmetics, clinical methods, and genetic approaches.
research Multiphoton Microscopic Imaging of Rabbit Dorsal Skin
Multiphoton microscopy effectively images rabbit skin structures in detail without staining and shows differences from human skin.