research Effect of Rubbing Application on the Skin Permeation of Active Ingredients from Lotion and Cream
Rubbing skin increases absorption of water-soluble drugs from lotions and creams, but not oil-soluble drugs.
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research Reflectance Spectroscopy for Noninvasive Evaluation of Hair Follicle Stage
Reflectance spectroscopy can noninvasively track hair growth stages by measuring skin reflectance and melanin changes.
research Update on the Treatment of Trichotillomania
Trichotillomania (TTM) is a challenging obsessive-compulsive disorder characterized by recurrent hair pulling, leading to hair loss or alopecia. Effective management involves both pharmacological and non-pharmacological strategies. Cognitive-behavioral therapy is a successful treatment, though not all patients opt for it. Alternative support tools like electronic devices, internet therapies, and microneedling are suggested. N-acetylcysteine and memantine are recommended as first-line therapies due to their safety, efficacy, and minimal adverse effects. Other medications such as fluoxetine, clomipramine, olanzapine, and naltrexone show limited and variable efficacy. The review highlights current treatment options for TTM.
research Integrated Safety Analysis of Ritlecitinib, an Oral JAK3/TEC Family Kinase Inhibitor, for the Treatment of Alopecia Areata from the ALLEGRO Clinical Trial Program
Ritlecitinib is safe and well-tolerated for treating alopecia areata in patients aged 12 and older.
research Segmental Hair Analysis as a Retrospective Testosterone Diary: Possibilities and Pitfalls
Segmental hair analysis can track testosterone over time but needs adjustments for sex, hair color, and washing frequency.
research Digital Influencers and the Spread of Irrational Drug Use
Social media influencers often promote self-medication, which can be dangerous without professional guidance.
research Retrospective Look at Cow-Calf Performance in Spring-Calving Dexter Cattle Scored for Winter Hair Shedding Level
Cows that shed more hair in winter have better reproductive success and their calves weigh more at weaning.
research Segmental Hair Analysis - A Retrospective Testosterone Diary?
Hair analysis can somewhat track past testosterone levels but is influenced by factors like hair washing, growth rate, sex, and hair color.
research Keratitis-Ichthyosis-Deafness Syndrome Caused by Missense Mutation in GJB2 Encoding Connexin 26 in a Chinese Patient
A Chinese man with KID syndrome had a new mutation in the GJB2 gene.
research The Acne-Treatment Potential of Cinnamomum Camphora Chvar. Borneol Essential Oil In Vitro and In Vivo
Borneol Essential Oil could be a natural and safe acne treatment.
research Association Between Stress and Bilateral Symmetrical Alopecia in Free-Ranging Formosan Macaques in a High-Population-Density Area
Stress likely causes hair loss in Formosan macaques.
research Effect of Needle Geometry on Insertion Force of Different Hair Implanters
Needle shape affects the force needed for hair implants, with certain shapes reducing the effort required.
research Upregulation of SERPINB3/B4 and S100A7-9 in Hidradenitis Suppurativa/Acne Inversa
Certain proteins are significantly increased in the skin of people with hidradenitis suppurativa.
research Enzyme Inhibitory Activities of Marine Sponges Against Cholinesterase and 5α-Reductase
Marine sponges from Tabuhan Island can inhibit enzymes linked to Alzheimer's and hair loss.
research Hair Growth Promoting Activity of Nothopanax Scutellarium Merr. Leaves
Nothopanax scutellarium leaves can promote hair growth but may mildly irritate the skin.
research A Comparison of the Purification Capacity of Five Plant Types Cultivated on Floating Beds for Restoration of Aquatic Environment
Canna indica is the best plant for water purification.
research Numerous Faces of Yellow Dots: Dermatoscopic Features in Various Types of Effluvium
Yellow dots look different in various hair loss conditions and can help diagnose them.
research Alopecia Areata in the United States: Outpatient Utilization and Common Prescribing Patterns
Two cosmetic lotions used day and night may be a good alternative to minoxidil for hair loss treatment with better cosmetic effects and tolerance.
research A Randomized, Blinded, Three-Arm, Multicenter Trial Comparing the Efficacy and Safety of Fluconazole Given Once Daily for 3 or 6 Weeks with Griseofulvin Given Once Daily for 6 Weeks in Pediatric Patients with Tinea Capitis
The two lotions used day and night may be a good alternative to minoxidil for hair loss treatment with better cosmetic effects and tolerance.
research Acute, Diffuse, And Total Alopecia
Two lotions used day and night may be a good alternative to minoxidil for hair loss, with better cosmetic effects and tolerance.
research Corrigendum to '3D Bioprinting of a Gelatin-Alginate Hydrogel for Tissue-Engineered Hair Follicle Regeneration'
Corrections were made to a previous work on 3D printing a gel-alginate mix for creating hair follicles, but the main finding - that this method can help grow hair - remains the same.
research Timing of Expression of the Core Clock Gene Bmal1 Influences Its Effects on Aging and Survival
The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
research How to Distinguish Medicalization from Over-Medicalization?
The article suggests using four questions to tell apart necessary medicalization from excessive medicalization, focusing on problem significance, social expectations, medical understanding, and effective resolution.
research In Search of Decoding the Syntax of the Bioelements in Human Hair: A Critical Overview
Hair analysis can show nutritional status and environmental exposure, with phosphorus being very stable in hair and differences found based on gender and conditions like depression and autism.
research Molecular Elements of the Regulatory Control of Keratin Filament Modulator AHF/Trichohyalin in the Hair Follicle
The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.
research Runx Family Genes in Tissue Stem Cell Dynamics
Runx genes are important for stem cell regulation and their roles in aging and disease need more research.
research OsUEV1B, a Ubc Enzyme Variant Protein, Is Required for Phosphate Homeostasis in Rice
OsUEV1B protein is essential for controlling phosphate levels in rice.
research Phytochemical Analysis of Eclipta Prostrata L. Leaves
Eclipta prostrata leaves contain various compounds with medicinal properties.
research Ethanol Extract of Asiasari Radix Preferentially Induces Apoptosis in G361 Human Melanoma Cells by Differential Regulation of p53
Asiasari radix extract may be a potential treatment for melanoma because it selectively triggers cell death in melanoma cells by affecting p53 regulation.
research Oral Presentation Abstracts
The conclusions are: fecal short-chain fatty acids may help prevent cancer, fiber intake can reduce obesity, weight loss is hard for obese people, low BMI cancer patients are more prone to chemotherapy side effects, intermittent fasting benefits gut health, cherry laurel has health benefits in rats, certain gene variations can increase stress in hair loss patients, fecal acids can affect blood sugar levels, cold agglutinin can affect blood test results in autoimmune patients, and people with Crohn's disease have higher levels of a certain chemical in their blood.