Acute, Diffuse, And Total Alopecia

    March 2005 in “ Journal of The American Academy of Dermatology ”
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    TLDR Two lotions used day and night may be a good alternative to minoxidil for hair loss, with better cosmetic effects and tolerance.
    The document presents findings from a study that evaluated the effectiveness of two cosmetic lotions, one containing a 5α-reductase inhibitor for daytime use and another containing an angiogenic active ingredient for nighttime use, in promoting hair growth in individuals with androgenetic alopecia (AGA). The study involved 125 male and female subjects who were divided into three groups: one using the separate day and night lotions (N/D), one using a mixture of both lotions (MIX), and one using 2% topical minoxidil (M). Over a 12-month period, with 7 hair samplings taken at 2-month intervals, results showed a statistically significant increase in hair weight for all three groups. The cosmetic lotions were preferred by subjects for their ease of application and penetration, and the N/D group showed the best hair effects. The study concluded that the daily application of the two lotions may be a good alternative to counteract hair loss, with better cosmetic effects and local tolerance than 2% minoxidil. The study was fully sponsored by Institut de Recherche Pierre Fabre.
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