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Stem cell niches are crucial for regulating stem cell behavior and tissue health, and their decline can impact aging and cancer.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hormone therapy for trans individuals is effective and generally safe in the short term.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Minoxidil boosts growth factor in hair cells, potentially promoting hair growth.

Some medicinal plants can help heal wounds and may lead to new treatments.

Zinc is crucial for growth and health in rats.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Cepharanthine is a well-tolerated drug with multiple medical uses, including anti-inflammatory and anti-cancer properties.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

The article concludes that the wool follicle is a valuable model for studying tissue interactions and has potential for genetic improvements in wool production.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Hair loss linked to higher heart disease risk in both men and women.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

One minoxidil-sensitive potassium channel exists in human hair follicles.

Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Women with type 1 diabetes often have polycystic ovary syndrome and excess male hormones, which are frequently undiagnosed.