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The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Hair follicle biology advancements may lead to better hair growth disorder treatments.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

VEGF helps hair grow and determines follicle size by increasing blood vessel growth.

Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.

Changing the environment around stem cells could help tissue repair, but it's hard to be precise and avoid side effects.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.

African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.

Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.

Targeting colon cancer stem cells might lead to better treatment results.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

Nerve signals are crucial for hair follicle stem cells to become skin stem cells and help in wound healing.

Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.

β-catenin is essential for stem cell activation and proliferation in hair follicles.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

The document concludes that the understanding of scar formation is incomplete and current prevention and treatment for hypertrophic scars and keloids are not fully effective.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

The article suggests managing interferon beta therapy side effects in MS with dose adjustments, medications, and patient education.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Apoptosis is essential for human skin development and forming a functional epidermis.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.