research Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition
The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.
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630-660 / 1000+ results research Impaired Notch-MKP-1 Signalling in Hidradenitis Suppurativa: An Approach to Pathogenesis by Evidence from Translational Biology
Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.
research Dermal Adipose Tissue Has High Plasticity And Undergoes Reversible Dedifferentiation In Mice
Dermal adipose tissue in mice can change and revert to help with skin health.
research Autoimmune Polyendocrine Syndrome Type 1: A Case Report from Bangladesh
A rare endocrine disorder, APS 1, was diagnosed in a 26-year-old man in Bangladesh.
research In Vitro and In Vivo Structure-Activity Relationships of Novel Androgen Receptor Ligands with Multiple Substituents in the B-Ring
Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.
research Novel PAX9 Mutation Associated with Syndromic Tooth Agenesis
A new PAX9 gene mutation causes missing teeth and hair problems, but not skin or nail issues.
research The Human Skin as a Hormone Target and an Endocrine Gland
Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
research Alopecia in Children
Most hair loss in children is caused by a few common conditions and is easy to diagnose, but rare types require careful evaluation.
research Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury
Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.
research Megestrol Acetate Increases the Proliferation, Migration, and Adipogenic Differentiation of Adipose-Derived Stem Cells via Glucocorticoid Receptor
Megestrol acetate helps fat-derived stem cells grow, move, and turn into fat cells through a specific receptor.
research Sparse Haplotype-Based Fine-Scale Local Ancestry Inference at Scale Reveals Recent Selection on Immune Responses
Recent selection on immune response genes was identified across seven ethnicities.
research Hypoparathyroidism as the Single Major Component for Decades of Autoimmune Polyglandular Syndrome Type 1
A man with hypoparathyroidism had other health issues that led to a diagnosis of a rare autoimmune disorder, APS-1.
research Male Pattern Hair Loss: Current Understanding
Genetics and hormones cause hair loss; finasteride treats it safely.
research The Clinical Management of Hirsutism
The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.
research Skin 3D Bioprinting: Applications in Cosmetology
3D bioprinting could improve skin repair and treat conditions like vitiligo and alopecia by precisely placing cells.
research Stem Cells in the Skin
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
research Abstracts
Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.
research Novel TMEM173 Mutation and the Role of Disease-Modifying Alleles
A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.
research Hardwiring Stem Cell Communication Through Tissue Structure
The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.
research Prolactin Delays Hair Regrowth in Mice
Prolactin slows down hair growth in mice.
research Hypersensitivity Reactions to Anticoagulant Drugs: Diagnosis and Management Options
Allergic reactions to blood thinners are rare but can be serious, requiring careful testing and alternative treatments.
research Is Dutasteride a Therapeutic Alternative for Amyotrophic Lateral Sclerosis?
Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.
research Modulating Mesenchymal Stem Cell Behavior Using Human Hair Keratin-Coated Surfaces
Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.
research Metabolic Regulation of Stem Cells in Aging
Eating less can improve stem cell function and increase lifespan.
research Stem Cells of the Hair Follicular Tissue: Application in Cell-Based Therapy for Vitiligo
Hair follicle stem cells could be used to treat the skin condition vitiligo.
research The Profibrogenic Role of Neutrophil Extracellular Traps in Stenotic Crohn's Disease: A New Antifibrotic Target?
Targeting NETs may help reduce fibrosis in Crohn's disease.
research Inhibition of Steroid 5 Alpha-Reductase with Finasteride: Sleep-Related Erections, Potency, and Libido in Healthy Men
Finasteride doesn't affect erections much, but may decrease libido in men.
research Exploring the Interplay Between Arsenic and Cutaneous Physiology, Pathology, and Regeneration
Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.
research Regenerative Medicine Approaches for Engineering a Human Hair Follicle
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
research Androgens and Human Hair Growth
Androgens can cause hair growth in some areas and hair loss on the scalp.