Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study reviewed the current state of intralesional therapy for keratoacanthoma, finding that while methotrexate, 5-fluorouracil, and interferon alpha are common agents, guidelines are still needed, and histopathological confirmation is advised to prevent misdiagnosis with squamous cell carcinoma.

This study describes a genetic mutation in the desmoglein 4 gene linked to localized autosomal recessive hypotrichosis in Pakistani families, showing similarities to animal models with similar hair loss conditions.

This study optimized the reaction conditions for the stereoselective hydrogenation of a compound used in manufacturing finasteride and dutasteride, improving the selectivity for the desired isomer.

This report observed that a male developed erythema multiforme linked to both topical and oral minoxidil use for androgenetic alopecia, supported by eruption recurrence with reapplication.

This review highlights the promising clinical outcomes of sacituzumab tirumotecan (sac-TMT), an antibody-drug conjugate for breast cancer that targets TROP2, demonstrating improved response rates and progression-free survival, with manageable safety concerns including primarily mild-to-moderate nausea and alopecia.

This study found that intron 3 VNTR polymorphism in the IL-4 gene may be associated with an increased risk of alopecia areata in the Turkish population.

This article discusses the introduction and market presence of the Italian hair product Kevis but presents no new clinical findings.

This article reviews approved treatments for androgenetic alopecia and reports no new research findings, highlighting the need for further studies.

In this study, researchers used conditional mouse models to show that inactivation of the Alx4 gene in specific cell lineages leads to craniofacial and limb defects without affecting postnatal survival, providing insights into Alx4's role in development and disease.

This study found that XP-endo Finisher R was approximately twice as effective as passive ultrasonic irrigation in removing root filling material from curved mesiobuccal canals of maxillary molars.

This study identified CYP3A4 as a key isozyme involved in the oxidative metabolism of finasteride in human liver microsomes.

This study found that VMAT hair-sparing WBRT partially preserved scalp hair at four weeks post-treatment without compromising symptomatic disease control in the short term, but reduced hair loss did not improve quality of life.

This systematic review found that toluidine blue may be valuable for diagnosing and treating specific skin tumors in the context of Mohs micrographic surgery, though literature on its use is limited and mostly qualitative.

This review discusses the pharmacological properties of 4-0-methylhonokiol from Magnolia species and reports no new experimental results, highlighting potential areas for future research.

Minoxidil 5% solution quickly improves hair growth and density with minimal side effects.

This case report describes successful treatment of a 7-year-old girl with gray patch tinea capitis using oral micronized griseofulvin and topical ketoconazole shampoo, resulting in complete clinical and microscopic clearance.

In this study, pre-treatment with steam towel, l-menthol, and CA-carpronium enhanced the absorption of minoxidil nanoparticles in mice, potentially increasing therapeutic efficiency without side effects.

Scalp micropigmentation is a process where tiny dots of pigment are tattooed onto the scalp to create the appearance of a shaved head or fuller hair.

Baricitinib helps with early hair regrowth in people with alopecia areata.

This study suggests that mouse keratin 6 isoforms, K6a and K6b, have overlapping but distinct expression profiles, differing notably in their expression in suprabasal cells and response to phorbol esters.

CD34 is a marker for isolating stem-like cells in mouse hair follicles.

Reflectance confocal microscopy can tell apart white dots on the scalp as either sweat gland ducts or hair follicle openings.

This abstract describes the opening of the ISHR’s 10th Annual Meeting in Modena and includes no new research findings.

This article highlights the potential of reflectance confocal microscopy for diagnosing and monitoring melasma treatments, and discusses new therapies using oral melatonin, glutathione, and resveratrol, as well as the growing interest in oral minoxidil for alopecia.

This study observed that vitamin D receptor expression in certain hair follicle cells varies throughout the murine hair cycle, suggesting a potential role for 1,25-dihydroxyvitamin D3 in hair follicle biology.

This study identified a mutation hotspot in the caracul (Ca) locus of mice, implicating the mK6irs1/Krt2-6g gene in hair formation and potentially human hair and skin diseases.

This preliminary study found that Melandrium firmum extract may promote hair growth and inhibit 5α-reductase, suggesting potential as a candidate for treating androgenetic alopecia.

This review discusses recent developments in targeted melanoma therapies, including BRAF/MEK/ERK pathway inhibitors and challenges like resistance and skin toxicities, but reports no new clinical results.