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Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

CRISPR/Cas9 gene-editing may effectively treat hair loss but requires more research for safe use.

Type I interferons play a key role in the development of various skin diseases.

A Chinese male with a new genetic mutation has a skin condition and severe urinary issues, with treatments having mixed success.

Azathioprine can cause severe blood issues and hair loss, needing careful monitoring and possible discontinuation.

The document concludes that early and accurate diagnosis of hair loss on the top of the scalp in Black men is important to distinguish CCCA from other types of hair loss.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Genes and epigenetic changes are important in the development of Polycystic Ovary Syndrome.

The KRTAP7-1 gene is very similar across different cattle and yak breeds and likely plays a role in hair strength and shape.

Certain skin proteins can form anchoring structures without the protein AMACO.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.

The endocannabinoid system affects oil production and inflammation in skin cells.

Mice with extra human KLK14 had hair and skin problems, including weaker cell bonds and inflammation, linked to Netherton syndrome.

Two different mutations in the vitamin D receptor gene cause different symptoms and responses to treatment in Lebanese patients with hereditary rickets.

The cause of Frontal fibrosing alopecia, a type of hair loss, is complex, likely involving immune responses and genetics, but is not fully understood.

The review suggests thorough evaluation and genetic testing for proper diagnosis and treatment of Chrousos syndrome.

A new gene mutation linked to a skin condition was found in a Spanish family.

When skin blisters, healing the wound is more important than growing hair, and certain stem cells mainly fix the blisters without helping hair growth.

Using 17-hydroxyprogesterone levels to diagnose nonclassic congenital adrenal hyperplasia can result in many incorrect diagnoses.

The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.

RSPO1 mutations in certain patients lead to skin cells that don't develop properly and are more likely to become invasive, increasing the risk of skin cancer.

Hair follicles are key to treating vitiligo and alopecia areata, but challenges exist.

Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.

Certain gene mutations can weaken the skin barrier and, when combined with environmental factors, lead to eczema and severe itching.

Genetic variations affecting skin structure play a key role in severe acne.

UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.

The document suggests a bacteria plays a significant role in acne rosacea and that white hair can regain color after transplant, meriting more research on reversing grey hair.

New genetic mutations linked to rare skin disorders were found in three newborns.