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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Hormone therapy can improve mental health and quality of life for people with gender dysphoria, but long-term effects need more research.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

Methionine restriction works better than betaine for treating CBS deficiency symptoms in mice.

DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.

Testosterone therapy seems safe for short-term use in postmenopausal women with low sexual desire, but more research on long-term effects is needed.

A hormone linked to collagen helps hair grow back in mice after chemotherapy, and may also prevent bone loss.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.

Zinc is essential for many body functions and imbalances can lead to health problems.

People with hidradenitis suppurativa often have lower vitamin D levels, weaker hip bones, and altered bone metabolism markers.

Higher free testosterone levels can increase bone density and decrease body fat but may raise the risk of prostate cancer, hair loss, and benign prostate enlargement.

Vitamin D helps regulate calcium levels in the body.

Testosterone and its metabolites have varied effects on different body systems, especially during puberty.

The treatment effectively reduced hair growth and was safe for patients with PCOS, but it needs better bleeding control.

Isotretinoin is a preferred treatment for severe acne, often leading to long-term improvement, but requires careful monitoring due to potential side effects.

Removing Mediator 1 from certain mouse cells causes teeth to grow hair instead of enamel.

Testosterone with finasteride improved muscle and bone health in men with spinal cord injury.

The Ayurvedic treatment helped a woman with PCOS, improving her symptoms and menstrual cycle.

In 2021, JAMA Dermatology published significant findings on skin conditions post-COVID vaccination, melanoma surveillance, atopic dermatitis treatments, and confirmed that sun protection does not harm bone health.

The patient with a misplaced pituitary gland and interrupted pituitary stalk is being treated with hormone replacement.

DHEA supplementation may improve quality of life, neuropsychological functions, and sexual satisfaction in individuals with adrenal insufficiency, but more research is needed to confirm its safety and effectiveness.

The consensus provided guidelines for treating the Female Athlete Triad and a system to decide when athletes can return to sports.

Androgen deprivation therapy for prostate cancer can cause sexual, physical, and psychological side effects, and doctors should manage these carefully.

Vitamin D and its receptor are essential for hair growth, cell regulation, immune function, and heart health.

Researchers created a mouse model for Cushing's syndrome to study glucocorticoid excess and potential treatments.