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The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

Stress can stop hair growth in mice, and treatments can reverse this effect.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

TRP channels in the skin are important for sensation and health, and targeting them could help treat skin disorders.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

New treatments targeting specific genes show promise for treating keratin disorders.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

A mother's PPARγ is crucial for preventing harmful milk that can cause inflammation and growth problems in babies.

Nerves and chemicals in the body can affect hair growth and loss.