This case report highlights a rare instance of minoxidil-induced pleuro-pericardial effusion with tamponade in a patient with end-stage renal disease on hemodialysis, which improved following pericardiocentesis and discontinuation of the drug.
30 citations
,
January 2024 This review explores and updates previous findings on the skin manifestations associated with diabetes, questioning some established signs while introducing additional cutaneous symptoms linked to the condition.
2 citations
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August 2002 in “British Journal of Ophthalmology” This article discusses the potential of intralesional cidofovir as a treatment for SCC and reports no systemic toxicity, but highlights surgical excision as the most reliable curative option.
November 2025 in “Undersea and Hyperbaric Medicine” This case report observed that a patient experienced worsening alopecia and scarring after medical ozone therapy, with subsequent improvement following surgical intervention and systemic hyperbaric oxygenation.
July 2004 in “Hair transplant forum international” This report describes an extremely rare case of arteriovenous fistula appearing after hair restoration surgery, observed in just one instance.
April 2026 in “Skin Appendage Disorders” This case report documents the first known occurrence of basal cell carcinoma at the site of repeated microneedling use for male androgenetic alopecia, underscoring the need for further studies on the long-term safety of such devices.
35 citations
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February 1993 in “International Journal of Dermatology” This report describes two cases where pemphigus lesions developed at sites of cosmetic procedures, suggesting these treatments might trigger the disease and should be distinguished from other post-surgery complications.
May 2023 in “Current Medicinal Chemistry” This review highlights the potential of microneedle devices in dermatology for conditions like skin aging and autoimmune skin diseases, emphasizing their ability to facilitate targeted drug delivery by creating temporary skin pathways.
55 citations
,
July 2016 in “Eye”
July 2012 in “Reactions Weekly” Minoxidil use was linked to a rare eye condition that improved after stopping the treatment.
January 2025 in “ARC Journal of Urology” This review reports that treatments for urological cancers, such as chemotherapy and immunotherapy, often result in significant dermatological side effects that negatively affect patients' quality of life and treatment adherence, highlighting a need for better management strategies and further research.
7 citations
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September 2018 in “Journal of cosmetic dermatology” This case report describes a patient who developed acute, painful lymphadenopathy after microneedling with platelet-rich plasma, suggesting a need to include this potential risk in patient consent forms and education.
6 citations
,
September 1988 in “Drug intelligence & clinical pharmacy” This report documents a case of dermatological toxicity associated with chronic minoxidil therapy, highlighting the emergence of a severe rash after three years of use, which recurred upon inadvertent rechallenge.
9 citations
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August 2014 in “Lupus” This report presents a case of a 17-year-old woman with systemic lupus erythematosus and systemic vasculitis, highlighting the importance of early diagnosis and timely referral for intensive treatment.
18 citations
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March 1974 in “Acta dermato-venereologica” Chronic kidney disease can cause skin and nail problems.
28 citations
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September 2016 in “Future oncology” In this study, a UK expert panel discussed strategies for managing common side effects of vismodegib, a hedgehog pathway inhibitor used for advanced basal cell carcinoma, concluding that adverse events like taste disturbances and muscle cramps can be effectively managed to optimize treatment duration.
Hair transplant surgery can have complications.
June 2026 in “Precision medicine and engineering.” In this study, researchers created a hydrogel that reduces oxidative stress and releases a pro-angiogenic drug in response to enzyme activity, which accelerated healing and improved tissue regeneration in chronic diabetic wounds during in vivo experiments.
14 citations
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April 2017 in “American Journal of Transplantation” This review examines nonmalignant skin toxicities from immunosuppressive and transplant-related medications, emphasizing the need for effective identification and management by care providers; it presents no new research findings.
60 citations
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February 2015 in “Biomaterials” In this study, immobilized VEGF selectively captured endothelial cells under various shear stresses, suggesting its potential for promoting endothelialization in vascular grafts or implanted tissues.
This case report describes the first instance of basal cell carcinoma developing at the site of repeated microneedling for androgenetic alopecia, highlighting the need for further safety studies.
September 2025 in “Case Reports in Ophthalmology” This case report suggests that even short-term use of topical minoxidil, as brief as one week, can induce central serous chorioretinopathy, which may resolve with medication discontinuation and observation.
April 2024 in “Rheumatology” This case report describes a 22-year-old woman whose initial manifestation of systemic lupus erythematosus was vision-threatening vaso-occlusive retinopathy, highlighting the need for early identification and multidisciplinary treatment.
This correspondence suggests that while patients with Raynaud phenomenon may develop connective tissue disorders, physicians should consider this possibility without assuming for certain that progression will occur.
16 citations
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May 1982 in “Postgraduate Medical Journal” Minoxidil can cause pericardial and pleural effusions with high protein content.
19 citations
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March 1990 in “Journal of Cardiovascular Pharmacology” Minoxidil affects rat fluid dynamics, altering pressure and circulation, improving blood flow and hair growth.
2 citations
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January 2006 in “PubMed” This study found that topical application of carpronium chloride led to arteriolar vasodilation and increased blood flow in rat mesenteric arterioles, without affecting systemic blood pressure.
1 citations
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April 1998 in “PubMed”
November 2019 in “Nosotchu” This case study describes a 21-year-old man who experienced a hemorrhagic stroke potentially linked to finasteride and minoxidil use for androgenic alopecia, emphasizing the need for thorough medication history in young stroke patients.
13 citations
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January 2021 in “The American journal of gastroenterology” In this study, sirolimus treatment reduced the size of venous malformations and improved anemia, transfusion dependence, and quality of life in patients with blue rubber bleb nevus syndrome, though mild adverse effects were reported.